Results 11 to 20 of about 384,029 (308)

Reovirus Low-Density Particles Package Cellular RNA

open access: yesViruses, 2021
Packaging of segmented, double-stranded RNA viral genomes requires coordination of viral proteins and RNA segments. For mammalian orthoreovirus (reovirus), evidence suggests either all ten or zero viral RNA segments are simultaneously packaged in a ...
Timothy W. Thoner   +3 more
doaj   +1 more source

Performance comparison of four types of target enrichment baits for exome DNA sequencing

open access: yesHereditas, 2021
Background Next-generation sequencing technology is developing rapidly and target capture sequencing has become an important technique. Several different platforms for library preparation and target capture with different bait types respectively are ...
Juan Zhou   +5 more
doaj   +1 more source

Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis

open access: yesCommunications Biology, 2021
Nakano et al. use high-speed AFM and cryo-EM to study influenza virus RNA synthesis in vitro. They observe the synthesis of two types of RNA: folded single stranded RNA associated to an intact viral ribonucleoprotein (vRNP) and looped, double stranded ...
Masahiro Nakano   +6 more
doaj   +1 more source

Contribution of Small RNA Pathway to Interactions of Rice with Pathogens and Insect Pests

open access: yesRice, 2021
Small RNAs (sRNAs) are mainly classified into microRNAs (miRNAs) and small interfering RNAs (siRNAs) according to their origin. miRNAs originate from single-stranded RNA precursors, whereas siRNAs originate from double-stranded RNA precursors that are ...
Qin Feng   +3 more
doaj   +1 more source

Double Stranded RNA in Human Seminal Plasma

open access: yesFrontiers in Genetics, 2017
Recently, human semen was shown to contain cell-free nucleic acids, such as DNA, long single stranded RNA, and small RNAs–miRNA and piRNA. The RNAs have been suggested to have potential biological roles as communication molecules between cells and in the
Maxim V. Zagoskin   +3 more
doaj   +1 more source

In vitro antiviral activity of a double-stranded RNA sodium salt-based medicinal product against SARS-CoV-2

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Innate immune activation in the early phases of COVID-19 infection and subsequent interferon induction may help control viral replication and protect cells not yet infected with SARS-CoV-2.
G. M. Ignatyev   +5 more
doaj   +1 more source

Human NLRP1 is a sensor for double-stranded RNA

open access: yesScience, 2020
A dsRNA detector in the immune toolkit Nod-like receptor (NLR) proteins recognize pathogen-associated molecular patterns within cells, which triggers the formation of signaling complexes called inflammasomes.
Stefan Bauernfried   +4 more
semanticscholar   +1 more source

Analysis of Double-Stranded RNA from Microbial Communities Identifies Double-Stranded RNA Virus-like Elements

open access: yesCell Reports, 2014
Double-stranded RNA (dsRNA) can function as genetic information and may have served as genomic material before the existence of DNA-based life. By developing a method to purify dsRNA, we have investigated the diversity of dsRNA in microbial populations ...
Carolyn J. Decker, Roy Parker
doaj   +1 more source

UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair

open access: yesNature Communications, 2021
R loops are formed when single-stranded RNA anneals to one strand of DNA, forming three-stranded structures containing DNA-RNA hybrids and the displaced non-template single-stranded DNA. Here the authors reveal that the DNA:RNA helicase UPF1 plays a role
Greg H. P. Ngo   +2 more
doaj   +1 more source

Double-Stranded RNA Technology to Control Insect Pests: Current Status and Challenges

open access: yesFrontiers in Plant Science, 2020
Exploiting the RNA interference (RNAi) gene mechanism to silence essential genes in pest insects, leading to toxic effects, has surfaced as a promising new control strategy in the past decade.
O. Christiaens   +3 more
semanticscholar   +1 more source

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