Background: Emerging viruses could be detected before reaching pandemic level if universal viral detection screening was routinely used. Double-stranded RNA (dsRNA) is the only common antigen across most viral families.
Kornthara Kawang +5 more
doaj +1 more source
A model for the force stretching double-stranded chain molecules
We modify and extend the recently developed statistical mechanical model for predicting the thermodynamic properties of chain molecules having noncovalent double-stranded conformations, as in RNA or ssDNA, and $\beta-$sheets in protein, by including the ...
Fei Liu +5 more
core +1 more source
Single-stranded endonuclease activity in the excretory--secretory products of Trichinella spiralis and Trichinella pseudospiralis [PDF]
A novel acidic extracellular single-stranded endonuclease was demonstrated for the first time in the excretory-secretory (E-S) products of 2 species of Trichinella. Unlike the double-stranded endonuclease reported earlier, the single-stranded molecule is
Chung, YYY, Ko, RCC, Mak, C
core +1 more source
Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients. [PDF]
Potent RNase activities were found in the serum of mammals but the physiological function of the RNases was never well illustrated, largely due to the caveats in methods of RNase activity measurement.
Weiyan Huang +6 more
doaj +1 more source
Reverse Genetics for Double-Stranded RNA Viruses
Resumen en inglès, ver archivo ...
H. Attoui +3 more
doaj +1 more source
High-Pressure-Sprayed Double Stranded RNA Does Not Induce RNA Interference of a Reporter Gene
In plants, RNA interference (RNAi) is an effective defense mechanism against pathogens and pests. RNAi mainly involves the micro RNA and the small interfering RNA (siRNA) pathways.
Veli Vural Uslu +4 more
doaj +1 more source
Why double-stranded RNA resists condensation [PDF]
The addition of small amounts of multivalent cations to solutions containing double-stranded DNA leads to inter-DNA attraction and eventual condensation. Surprisingly, the condensation is suppressed in double-stranded RNA, which carries the same negative charge as DNA, but assumes a different double helical form.
Tolokh, Igor S. +7 more
openaire +3 more sources
Production of a Discrete, Infectious, Double-stranded DNA by Reverse Transcription in Virions of Moloney Murine Leukemia Virus [PDF]
One of the most unique viral replication schemes is that of the retroviruses (a class that includes the RNA tumor viruses). These viruses synthesize a double-stranded (DS) DNA copy of their single-stranded (SS) RNA genome as the initial event following ...
Baltimore, D. +3 more
core +1 more source
Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site [PDF]
RNA editing by members of the ADAR (adenosine deaminase that acts on RNA) enzyme family involves hydrolytic deamination of adenosine to inosine within the context of a double-stranded pre-mRNA substrate.
Collins, Cynthia H. +2 more
core +1 more source
Double-stranded RNA elements associated with the MVX disease of Agaricus bisporus [PDF]
Double-stranded RNA (dsRNA) has been isolated from Agaricus bisporus fruit bodies exhibiting a wide range of disease symptoms. The symptoms which occurred singularly or in combination included; bare cropping areas on commercial beds (primordia disruption)
Adie, Bruce A. T. +4 more
core +1 more source

