Performance comparison of four types of target enrichment baits for exome DNA sequencing
Background Next-generation sequencing technology is developing rapidly and target capture sequencing has become an important technique. Several different platforms for library preparation and target capture with different bait types respectively are ...
Juan Zhou +5 more
doaj +1 more source
Method for assigning double-stranded RNA structures
Trevor S. Brown, Philip C. Bevilacqua
doaj +3 more sources
RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]
Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
core +6 more sources
Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis
Nakano et al. use high-speed AFM and cryo-EM to study influenza virus RNA synthesis in vitro. They observe the synthesis of two types of RNA: folded single stranded RNA associated to an intact viral ribonucleoprotein (vRNP) and looped, double stranded ...
Masahiro Nakano +6 more
doaj +1 more source
Contribution of Small RNA Pathway to Interactions of Rice with Pathogens and Insect Pests
Small RNAs (sRNAs) are mainly classified into microRNAs (miRNAs) and small interfering RNAs (siRNAs) according to their origin. miRNAs originate from single-stranded RNA precursors, whereas siRNAs originate from double-stranded RNA precursors that are ...
Qin Feng +3 more
doaj +1 more source
Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells [PDF]
Circulating RNA may result from excessive cell damage or acute viral infection and can interact with vascular endothelial cells. Despite the obvious clinical implications associated with the presence of circulating RNA, its pathological effects on ...
Heinemann, Akos +46 more
core +1 more source
Double-stranded RNA elements associated with the MVX disease of Agaricus bisporus [PDF]
Double-stranded RNA (dsRNA) has been isolated from Agaricus bisporus fruit bodies exhibiting a wide range of disease symptoms. The symptoms which occurred singularly or in combination included; bare cropping areas on commercial beds (primordia disruption)
Adie, Bruce A. T. +4 more
core +1 more source
Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses:Implications for virus evolution and host persistence [PDF]
Discrete RNA secondary and higher-order structures, typically local in extent, play a fundamental role in RNA virus replication. Using new bioinformatics analysis methods, we have identified genome-scale ordered RNA structure (GORS) in many genera and ...
Evans, David J +5 more
core +1 more source
Double Stranded RNA in Human Seminal Plasma
Recently, human semen was shown to contain cell-free nucleic acids, such as DNA, long single stranded RNA, and small RNAs–miRNA and piRNA. The RNAs have been suggested to have potential biological roles as communication molecules between cells and in the
Maxim V. Zagoskin +3 more
doaj +1 more source
UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair
R loops are formed when single-stranded RNA anneals to one strand of DNA, forming three-stranded structures containing DNA-RNA hybrids and the displaced non-template single-stranded DNA. Here the authors reveal that the DNA:RNA helicase UPF1 plays a role
Greg H. P. Ngo +2 more
doaj +1 more source

