Results 31 to 40 of about 384,029 (308)

A Rapid Method for Sequencing Double-Stranded RNAs Purified from Yeasts and the Identification of a Potent K1 Killer Toxin Isolated from Saccharomyces cerevisiae

open access: yesViruses, 2019
Mycoviruses infect a large number of diverse fungal species, but considering their prevalence, relatively few high-quality genome sequences have been determined.
Angela M. Crabtree   +6 more
doaj   +1 more source

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

open access: yesNature, 2018
Mitochondria are descendants of endosymbiotic bacteria and retain essential prokaryotic features such as a compact circular genome. Consequently, in mammals, mitochondrial DNA is subjected to bidirectional transcription that generates overlapping ...
Ashish Dhir   +17 more
semanticscholar   +1 more source

Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA

open access: yesOpen Biology, 2021
Endonuclease V is highly conserved, both structurally and functionally, from bacteria to humans, and it cleaves the deoxyinosine-containing double-stranded DNA in Escherichia coli, whereas in Homo sapiens it catalyses the inosine-containing single ...
Megumi Endo   +4 more
doaj   +1 more source

Rotavirus infection induces transient pancreatic involution and hyperglycemia in weanling mice. [PDF]

open access: yesPLoS ONE, 2014
Rotavirus is a ubiquitous double-stranded RNA virus responsible for most cases of infantile gastroenteritis. It infects pancreatic islets in vitro and is implicated as a trigger of autoimmune destruction of islet beta cells leading to type 1 diabetes ...
Margo C Honeyman   +5 more
doaj   +1 more source

A phagocytic route for uptake of double-stranded RNA in RNAi. [PDF]

open access: yesPLoS ONE, 2011
RNA interference (RNAi) has a range of physiological functions including as a defence mechanism against viruses. To protect uninfected cells in a multicellular organism, not only a cell-autonomous RNAi response is required but also a systemic one ...
João J E Rocha   +3 more
doaj   +1 more source

Sensitivity and specificity of anti-double-stranded RNA immunofluorescence for universal detection of viral infection in respiratory specimens

open access: yesHeliyon, 2021
Background: Emerging viruses could be detected before reaching pandemic level if universal viral detection screening was routinely used. Double-stranded RNA (dsRNA) is the only common antigen across most viral families.
Kornthara Kawang   +5 more
doaj   +1 more source

Characterization of Supercoiled Double-Stranded RNA, and Comparison to Double-Stranded DNA [PDF]

open access: yesBiophysical Journal, 2011
While the mechanical properties of double-stranded DNA have been intensely studied using various single molecule assays, much less is known about double-stranded RNA (dsRNA). dsRNA is important in Biology as it forms the hereditary material for a number of viruses, and is also central to the RNA mediated gene-silencing pathway.
Skinner, Gary M.   +4 more
openaire   +1 more source

Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients. [PDF]

open access: yesPLoS ONE, 2014
Potent RNase activities were found in the serum of mammals but the physiological function of the RNases was never well illustrated, largely due to the caveats in methods of RNase activity measurement.
Weiyan Huang   +6 more
doaj   +1 more source

A deletion mutant of L-A double-stranded RNA replicates like M1 double-stranded RNA [PDF]

open access: yesJournal of Virology, 1988
X double-stranded RNA (dsRNA) is a 0.52-kilobase dsRNA molecule that arose spontaneously in a nonkiller strain of Saccharomyces cerevisiae originally containing L-A and L-BC dsRNAs (L-BC is the same size as L-A but shares no homology with it). X hybridized with L-A, and direct RNA sequencing of X showed that the first 5' 25 base pairs (of the X ...
R, Esteban, R B, Wickner
openaire   +2 more sources

Reverse Genetics for Double-Stranded RNA Viruses

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2009
Resumen en inglès, ver archivo ...
H. Attoui   +3 more
doaj   +1 more source

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