Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
RNA dysfunction in age-related macular degeneration: the role of U1 snRNP complex and neurodegenerative diseases. [PDF]
Bottos JM +5 more
europepmc +1 more source
Recovery From Anorexia Nervosa: A Concept Analysis
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley +1 more source
Correction to 'Long Noncoding RNA Highly Upregulated in Liver Cancer Promotes Epithelial-to-Mesenchymal Transition Process in Oral Squamous Cell Carcinoma'. [PDF]
europepmc +1 more source
Unraveling Obesity: A Five-Year Integrative Review of Transcriptomic Data. [PDF]
Tarbeeva S +5 more
europepmc +1 more source
Novel Liquid Biopsy in Gastrointestinal Cancers
ABSTRACT Gastrointestinal (GI) cancers represent a significant global health burden, being among the leading causes of cancer‐related deaths. The prognosis for patients remains unsatisfactory, largely because most cancers are detected at advanced stages.
Li‐Chun Chang +2 more
wiley +1 more source
ELF18-INDUCED LONG NONCODING RNA 19 attenuates PAMP-induced callose deposition by modulating UDP-glycosyltransferase 71B6-associated ABA levels. [PDF]
Seo JS +9 more
europepmc +1 more source
Structural variation drives rhizome innovation and adaptive divergence in sister Medicago species
Chromosome‐scale genome analysis, population resequencing, stress‐responsive transcriptomes and functional assays showed that coding and regulatory structural variants, especially gene duplications and noncoding presence‐absence variants, underlie rhizome formation in alpine Medicago archiducis‐nicolai and contrasting xeric adaptation in its non ...
Hongyin Hu +14 more
wiley +1 more source
Expression of Concern for JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. [PDF]
Wang S +24 more
europepmc +1 more source

