Beyond the Exome: The Role of Noncoding and Regulatory Variants in Monogenic Diseases. [PDF]
Moustakli E +5 more
europepmc +1 more source
Drought priming increased the tolerance of Nicotiana tabacum to severe, recurring drought stress by modulating the expression of stress‐related genes via long non‐coding RNAs (lncRNAs), which acted as competing endogenous RNAs (ceRNAs) for microRNAs (miRNAs) and messenger RNAs (mRNAs).
Fatma Aydinoglu, Elif Yalvac
wiley +1 more source
So Fragile, So Human: Noncoding DNA Regions Orchestrating Gene Expression Involved in Neurodevelopmental Disorders and in Human Brain Evolution. [PDF]
Marenco C +14 more
europepmc +1 more source
circRMST (hsa_circ_0099634) is by far the most abundant isoform from the RMST locus. It is highly expressed in cancer cells throughout ependymoma patient samples and is located in the cytoplasm. circRMST knockdown causes cell cycle arrest and induces differentiation, and it is a marker for poor prognosis. The figure is made using BioRender.
Ulvi Ahmadov +6 more
wiley +1 more source
Intronic polyadenylation-derived long noncoding RNA modulates nucleolar integrity and function. [PDF]
Mallick S +5 more
europepmc +1 more source
Three closely linked X‐chromosomal genes potentially control sex determination in Cannabis sativa
Summary Sex determination mechanisms in dioecious plants remain poorly understood yet offer an excellent model system to study genetic changes underlying morphological evolution. We investigated the genetic basis of sex determination in Cannabis sativa, combining quantitative trait locus mapping in a segregating population, comparative transcriptomics ...
Matteo Toscani +8 more
wiley +1 more source
Orchestrating HFpEF: How Noncoding RNAs Drive Pathophysiology and Phenotypic Outcomes. [PDF]
Alifragki A +10 more
europepmc +1 more source
Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos +2 more
wiley +1 more source
Aberrantly expressed long noncoding RNAs in adipose-derived mesenchymal stem cells differentiation to nucleus pulposus-like cells. [PDF]
Zhu J +8 more
europepmc +1 more source

