Results 211 to 220 of about 223,182 (263)

Vaccinia-related kinase 1/snail family transcriptional repressor 1 regulates epithelial-mesenchymal transition and inflammation in proliferative vitreoretinopathy. [PDF]

Int J Ophthalmol
Ying Y, Liao X.
europepmc   +1 more source

Tea polyphenols suppress the malignant progression of renal cancer cells by targeting Nosip. [PDF]

Transl Androl Urol
Wang J, Huang Z, Yang D, Gao J, Xu Q, Dai M, Xia J, Ma J, Pan X.   +8 more
europepmc   +1 more source

Synthetic short RNA in cancer. [PDF]

Front Oncol
Tomita T, Minagawa K, Hiratsuka S.
europepmc   +1 more source

RNF112 mediates immunosuppression to inhibit the proliferation of cervical cancer by Foxm1. [PDF]

Transl Cancer Res
Pan H, Bao L, Shi W, Wan J.
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Azide-functionalized SpCas9 enables generation of site-selective and bioactive Cas9-siRNA conjugates.

Chem Commun (Camb)
Wilbie D, Timmers M, Kogkalidou A, Hebels ER, Sweet IR, Maas-Bakker R, Bosman E, de Jong OG, Vermonden T, Mastrobattista E.   +9 more
europepmc   +1 more source

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Chemical Modification of Small Interfering RNA

2011
Chemically synthesized siRNAs are widely used for gene silencing. For in vitro applications, stability, delivery, and immunological issues are rarely problematic, but for in vivo applications the situation is different. Limited stability, undesirable pharmacokinetic behaviour, and unanticipated side effects from the immune system call for more careful ...
Bramsen, Jesper Bertram, Kjems, Jørgen; id_orcid 0000-0003-4128-9317   +1 more
openaire   +2 more sources

RNA Interference and Small Interfering RNAs

ChemBioChem, 2001
The term aRNA interferenceo (RNAi) was coined after the groundbreaking discovery that injection of double-stranded RNA (dsRNA) into the nematode Caenorhabditis elegans leads to specific silencing of genes highly homologous in sequence to the delivered dsRNA.
openaire   +3 more sources