Results 31 to 40 of about 498,663 (149)
Transcriptomic Analysis of Gene Networks Regulated by U11 Small Nuclear RNA in Bladder Cancer
Small nuclear RNA is a class of non-coding RNA that widely exist in the nucleus of eukaryotes. Accumulated evidences have shown that small nuclear RNAs are associated with the regulation of gene expression in various tumor types.
Zhenxing Wang+23 more
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The epitranscriptome of small non-coding RNAs
Small non-coding RNAs are short RNA molecules and involved in many biological processes, including cell proliferation and differentiation, immune response, cell death, epigenetic regulation, metabolic control.
Xiaoyu Li, Jinying Peng, Chengqi Yi
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The disease resistance protein SNC1 represses the biogenesis of microRNAs and phased siRNAs
A small RNA-based signaling cascade prevents the induction of plant resistance genes (R-genes) in the absence of pathogen challenge. Here Cai et al.
Qiang Cai+9 more
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Circulating miRNAs, isomiRs and small RNA clusters in human plasma and breast milk. [PDF]
Circulating small RNAs, including miRNAs but also isomiRs and other RNA species, have the potential to be used as non-invasive biomarkers for communicable and non-communicable diseases.
Mercedes Rubio+12 more
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Long Noncoding RNAs in Metabolic Syndrome Related Disorders
Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (
Magdalena Losko+2 more
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PARN and TOE1 Constitute a 3′ End Maturation Module for Nuclear Non-coding RNAs
Summary: Poly(A)-specific ribonuclease (PARN) and target of EGR1 protein 1 (TOE1) are nuclear granule-associated deadenylases, whose mutations are linked to multiple human diseases.
Ahyeon Son, Jong-Eun Park, V. Narry Kim
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Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression, yet how this process is regulated by oncogenic signal remains largely unknown.
SiSi Li+30 more
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Conjoined use of EM and NMR in RNA structure refinement. [PDF]
More than 40% of the RNA structures have been determined using nuclear magnetic resonance (NMR) technique. NMR mainly provides local structural information of protons and works most effectively on relatively small biomacromolecules.
Zhou Gong+2 more
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Nuclear pore complex protein mediated nuclear localization of dicer protein in human cells.
Human DICER1 protein cleaves double-stranded RNA into small sizes, a crucial step in production of single-stranded RNAs which are mediating factors of cytoplasmic RNA interference. Here, we clearly demonstrate that human DICER1 protein localizes not only
Yoshinari Ando+14 more
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Tumor educated platelet: the novel BioSource for cancer detection
Platelets, involved in the whole process of tumorigenesis and development, constantly absorb and enrich tumor-specific substances in the circulation during their life span, thus called “Tumor Educated Platelets” (TEPs).
Shanshan Ding+2 more
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