Results 21 to 30 of about 218,333 (309)

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor. [PDF]

, 2016
Rocaglamide A (RocA) typifies a class of protein synthesis inhibitors that selectively kill aneuploid tumour cells and repress translation of specific messenger RNAs.
Floor, Stephen N, Ingolia, Nicholas T, Iwasaki, Shintaro   +2 more
core   +1 more source

Novel positive-sense, single-stranded RNA (+ssRNA) virus with di-cistronic genome from intestinal content of freshwater carp (Cyprinus carpio). [PDF]

PLoS ONE, 2011
A novel positive-sense, single-stranded RNA (+ssRNA) virus (Halastavi árva RNA virus, HalV; JN000306) with di-cistronic genome organization was serendipitously identified in intestinal contents of freshwater carps (Cyprinus carpio) fished by line-fishing
Ákos Boros, Péter Pankovics, Peter Simmonds, Gábor Reuter   +3 more
doaj   +1 more source

The Human Pregnancy-Specific Glycoprotein Genes are Tightly Linked on the Long Arm of Chromosome 19 and are Coordinately Expressed [PDF]

, 1990
The pregnancy-specific glycoprotein (PSG) genes encode a group of proteins which are found in large amounts in placenta and maternal serum. In situ hybridization analyses of metaphase chromosomes reveal that all the human pregnancy-specific glycoprotein (
Barnett, Barnett, Barnett, Benton, Bohn, Chan, Chomczynski, Feinberg, Fiddes, Grunert, Hefta, Hinoda, Jean, Kamarck, Khan, Khan, Kolbinger, Lathe, Lin, Maniatis, Neumaier, Niemann, Oikawa, Oikawa, Oikawa, Paxton, Perry, Rooney, Rudert, Sanger, Streydio, Takami, Tatarinov, Thompson, Thompson, Thompson, Watanabe, Watanabe, Willcocks, Zimmermann, Zimmermann   +40 more
core   +1 more source

The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen [PDF]

, 2011
Increased brain α-synuclein (SNCA) protein expression resulting from gene duplication and triplication can cause a familial form of Parkinson's disease (PD).
Bandyopadhyay, Sanghamitra, Cahill, Catherine M., Castelvetri, Ippolita Cantuti, Greig, Nigel H., Huang, Xudong, Lahiri, Debomoy K., Maccecchini, Maria L., Mikkilineni, Sohan, Rogers, Jack T., Smith, Deborah H.   +9 more
core   +1 more source

circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p

Frontiers in Cardiovascular Medicine, 2021
Circular RNA (circRNA) is a subclass of non-coding RNAs that enables the circular transcripts resistant to the exonuclease digestion. Iron homeostasis is essential for the body to maintain normal physiological functions.
Haoyuan Zheng, Lin Shi, Changci Tong, Yunen Liu, Yunen Liu, Mingxiao Hou, Mingxiao Hou, Mingxiao Hou   +7 more
doaj   +1 more source

The potential for reassortment between Oropouche and Schmallenberg Orthobunyaviruses [PDF]

, 2017
A number of viruses within the Peribunyaviridae family are naturally occurring reassortants, a common phenomenon for segmented viruses. Using a minigenome-reporter and virus-like particle (VLP) production assay, we have accessed the potential of ...
Elliott, Richard M., Olszanski Acrani, Gustavo, Shi, Xiaohong, Tilston-Lunel, Natasha L.   +3 more
core   +1 more source

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Afar D. E. H., Audette M., Baniyash M., Berling B., Culic O., Elsen P., Felgner P. L., Fiddes J. C., Knapp W., Kolbinger F., Kuroki M., Kuroki M., Kuroki M., Lin S.-H., Lucas K., Margolis R. N., McCuaig K., Nap M., Neumaier M., Ng S. Y., Oikawa S., Oikawa S., Paxton R., Pelegrin A., Raskind W. H., Rojas M., Sambrook J. E., Schwarz K., Shively J. E., Skubitz K. M., Southern P. J., Thompson J. A., Thompson J. A., Turbide C., Tynan K., Watt S. M., Woodgett J. R., Zhou H.   +37 more
core   +2 more sources

Regulatory RNAs: Have mRNA Untranslated Regions Joined the Party?

PLoS Medicine, 2008
Thomas Hughes and Pamela Jones discuss the implications of a new study on the 5' non-coding region of vascular endothelial growth factor mRNA and its influence on gene expression.
Thomas A Hughes, Pamela F Jones
openaire   +3 more sources

U4 at the 3' UTR of PB1 segment of H5N1 influenza virus promotes RNA polymerase activity and contributes to viral pathogenicity.

PLoS ONE, 2014
The viral RNA-dependent RNA polymerase has been found to contribute to efficient replication in mammalian systems and to the high pathogenicity of H5N1 influenza A virus in humans and other mammals. The terminal untranslated regions of the viral segments
Wei Sun, Jing Li, Pengfei Han, Yinhui Yang, Xiaoping Kang, Yuchang Li, Jiaming Li, Yu Zhang, Xiaoyan Wu, Tao Jiang, Chengfeng Qin, Yi Hu, Qingyu Zhu   +12 more
doaj   +1 more source

Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]

PLoS Genetics, 2010
The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng, Paul Ryvkin, Fan Li, Isabelle Dragomir, Otto Valladares, Jamie Yang, Kajia Cao, Li-San Wang, Brian D Gregory   +8 more
doaj   +1 more source