Nature Communications, 2020 G-quadruplexes (G4s) are secondary structures that can form in both DNA and RNA from guanine-rich sequences which are enriched in untranslated regions (UTRs). Here, Lee et al.
David S. M. Lee +2 more
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The 5 ' untranslated region of protein kinase C delta directs translation by an internal ribosome entry segment that is most active in densely growing cells and during apoptosis. [PDF]
, 2002 Protein kinase Cdelta (PKCdelta) is a member of the PKC family of phospholipid-dependent serine/threonine kinases and is involved in cell proliferation, apoptosis, and differentiation.
Morrish, B.C., Rumsby, M.G.
core +2 more sources
Tunable protein synthesis by transcript isoforms in human cells
eLife, 2016 Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated ...
Stephen N Floor, Jennifer A Doudna
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Transcription termination and antitermination of bacterial CRISPR arrays
eLife, 2020 A hallmark of CRISPR-Cas immunity systems is the CRISPR array, a genomic locus consisting of short, repeated sequences (‘repeats’) interspersed with short, variable sequences (‘spacers’). CRISPR arrays are transcribed and processed into individual CRISPR
Anne M Stringer +4 more
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Improved ontology for eukaryotic single-exon coding sequences in biological databases [PDF]
, 2018 Indexación: Scopus.Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term 'single-exon
Clausen, P. +4 more
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Keratinocyte differentiation-dependent human papillomavirus gene regulation [PDF]
, 2017 Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte.
Graham, Sheila V.
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Developmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium
Cell Reports, 2023 Summary: The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic development in metazoans. However, it is currently unknown whether similar processes exist in unicellular eukaryotes. The ciliate Paramecium tetraurelia harbors
Therese Solberg +3 more
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Protonatable Hairpins Are Conserved in the 5'-Untranslated Region of Tymovirus RNAs [PDF]
Nucleic Acids Research, 1996 The secondary structures of the 5'-untranslated region (5'-UTR) of five different tymoviruses have been determined by structure probing, computer prediction and sequence comparison. Despite large sequence differences, there are remarkable similarities in the secondary structure.
Hellendoorn, K. +3 more
openaire +4 more sources
THE CELLULAR RECEPTOR (CD4) OF THE HUMAN IMMUNODEFICIENCY VIRUS IS EXPRESSED ON NEURONS AND GLIAL CELLS IN HUMAN BRAIN [PDF]
, 1987 The peculiar tropism of the human immunodeficiency virus (HIV) for T helper lymphocytes can be explained by a specific interaction between the virus and the CD4 molecule on these cells (1, 2).
Funke, Ilona +4 more
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mSphere, 2021 Juvenile pacific oysters have been subject in recent years to summer mortality episodes with deep economic consequences.
Xing Luo +3 more
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