Results 21 to 30 of about 1,113,600 (301)
RNA Viral Community in Human Feces: Prevalence of Plant Pathogenic Viruses [PDF]
The human gut is known to be a reservoir of a wide variety of microbes, including viruses. Many RNA viruses are known to be associated with gastroenteritis; however, the enteric RNA viral community present in healthy humans has not been described.
Altschul +55 more
core +5 more sources
Molecular basis of specific viral RNA recognition and 5′-end capping by the Chikungunya virus nsP1
Summary: Many viruses encode RNA-modifying enzymes to edit the 5′ end of viral RNA to mimic the cellular mRNA for effective protein translation, genome replication, and evasion of the host defense mechanisms.
Kuo Zhang +7 more
doaj +1 more source
The advent of reverse genetic approaches to manipulate the genomes of both positive (+) and negative (-) sense RNA viruses allowed researchers to harness these genomes for basic research. Manipulation of positive sense RNA virus genomes occurred first largely because infectious RNA could be transcribed directly from cDNA versions of the RNA genomes ...
Mark A, Mogler, Kurt I, Kamrud
openaire +2 more sources
RNA Silencing and Plant Viral Diseases
RNA silencing plays a critical role in plant resistance against viruses, with multiple silencing factors participating in antiviral defense. Both RNA and DNA viruses are targeted by the small RNA-directed RNA degradation pathway, with DNA viruses being ...
Ming-Bo Wang +3 more
doaj +1 more source
Perspectives on Viral RNA Genomes and the RNA Folding Problem
Viral RNA genomes change shape as virus particles disassemble, form replication complexes, attach to ribosomes for translation, evade host defense mechanisms, and assemble new virus particles.
Susan J. Schroeder
doaj +1 more source
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
Hepatitis C virus (HCV) genome multiplication requires the concerted action of the viral RNA, host factors and viral proteins. Recent studies have provided information about the requirement of specific viral RNA motifs that play an active role in the ...
Encarnación Martinez-Salas +1 more
doaj +1 more source
Virus-derived DNA drives mosquito vector tolerance to arboviral infection
Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of ...
Bertsy Goic +10 more
doaj +1 more source
Functional RNA Elements in the Dengue Virus Genome
Dengue virus (DENV) genome amplification is a process that involves the viral RNA, cellular and viral proteins, and a complex architecture of cellular membranes.
Andrea V. Gamarnik +2 more
doaj +1 more source
Viral RNA at two stages of reovirus infection is required for the induction of necroptosis [PDF]
Necroptosis, a regulated form of necrotic cell death, requires the activation of the RIP3 kinase. Here, we identify that infection of host cells with reovirus can result in necroptosis.
Berger, Angela K +6 more
core +2 more sources

