Results 21 to 30 of about 2,788,248 (339)
Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
Nature Reviews Microbiology, 2016 Aartjan J W Te Velthuis, Ervin Fodor
exaly +2 more sources
Viral RNA as a Branched Polymer
, 2023 24 pages, 9 ...
Vaupotič, Domen +4 more
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A discontinuous RNA platform mediates RNA virus replication: building an integrated model for RNA-based regulation of viral processes. [PDF]
PLoS Pathogens, 2009 Plus-strand RNA viruses contain RNA elements within their genomes that mediate a variety of fundamental viral processes. The traditional view of these elements is that of local RNA structures.
Baodong Wu +5 more
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Poly(rC)-Binding Protein 1 Limits Hepatitis C Virus Virion Assembly and Secretion
Viruses, 2022 The hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding protein, poly(rC)-binding protein 1 (PCBP1), was previously reported to bind to the 5 ...
Sophie E. Cousineau +2 more
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Nucleocapsid Structure of Negative Strand RNA Virus
Viruses, 2020 Negative strand RNA viruses (NSVs) include many important human pathogens, such as influenza virus, Ebola virus, and rabies virus. One of the unique characteristics that NSVs share is the assembly of the nucleocapsid and its role in viral RNA synthesis ...
Ming Luo +2 more
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RNA Interference for Viral Infections [PDF]
Current Drug Targets, 2012 The treatment of viral infections has relied on pre-emptive vaccination or use of a limited range of anti-viral drugs. However, the majority of viruses have no available drugs and treatment is merely supportive. RNA interference (RNAi) offers the ability to directly and rapidly treat virus infections via the targeting of viral genes.
Blake, Stephen J. +2 more
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Frontiers in Cell and Developmental Biology, 2022 Viruses package host RNAs in their virions which are associated with a range of functions in the viral life cycle. Previous transcriptomic profiling of host RNA packaging mostly focused on retroviruses.
Noah Peña +21 more
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A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]
, 2019 Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D. +2 more
core +1 more source
Uirusu, 2009 Many lines of recent evidence indicate that non-coding RNAs including micro RNAs (miRNAs) and small interfering RNAs (siRNAs) play an important role in the control of gene expression in diverse cellular processes and in defense responses against molecular parasites such as viruses and transposons.
Hiro-oki, Iwakawa, Testuro, Okuno
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Journal of Virology, 2018 Activation of innate immunity is essential for host cells to restrict the spread of invading viruses and other pathogens. MAVS plays a critical role in innate immune response to RNA viral infection. In this study, we demonstrated that TRIM21 targets MAVS
Binbin Xue +8 more
semanticscholar +1 more source