Results 31 to 40 of about 2,788,248 (339)
Regulation of RNA Virus Processes by Viral Genome Structure
Proceedings, 2020 The genomes of RNA viruses contain a variety of RNA sequences and structures that regulate different steps in virus reproduction. Events that are controlled by RNA elements include (i) the translation of viral proteins, (ii) the replication of viral RNA ...
K. Andrew White
doaj +1 more source
Novel ATP-independent RNA annealing activity of the dengue virus NS3 helicase. [PDF]
PLoS ONE, 2012 The flavivirus nonstructural protein 3 (NS3) bears multiple enzymatic activities and represents an attractive target for antiviral intervention. NS3 contains the viral serine protease at the N-terminus and ATPase, RTPase, and helicase activities at the C-
Leopoldo G Gebhard +2 more
doaj +1 more source
Frontiers in Microbiology, 2019 Non-segmented negative strand (NNS) RNA viruses belonging to the order Mononegavirales are highly diversified eukaryotic viruses including significant human pathogens, such as rabies, measles, Nipah, and Ebola.
T. Ogino, T. Green
semanticscholar +1 more source
Viral suppression of RNA silencing [PDF]
Science China Life Sciences, 2012 يلعب إسكات الجينات (إسكات الحمض النووي الريبي) دورًا أساسيًا في الدفاع المضاد للفيروسات في النباتات والفطريات واللافقاريات. تقوم الفيروسات بتشفير البروتينات التي تمنع إسكات الجينات لمواجهة دفاع المضيف. تم تحديد المثبطات الفيروسية لإسكات الحمض النووي الريبي (RSVs) من جميع الفيروسات النباتية تقريبًا التي تولد وبعض فيروسات الحشرات والثدييات. كشفت الدراسات
Lin Jiang, Chunhong Wei, Yang Li
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Viral RNA at two stages of reovirus infection is required for the induction of necroptosis [PDF]
, 2017 Necroptosis, a regulated form of necrotic cell death, requires the activation of the RIP3 kinase. Here, we identify that infection of host cells with reovirus can result in necroptosis.
Berger, Angela K +6 more
core +2 more sources
Perspectives on Viral RNA Genomes and the RNA Folding Problem
Viruses, 2020 Viral RNA genomes change shape as virus particles disassemble, form replication complexes, attach to ribosomes for translation, evade host defense mechanisms, and assemble new virus particles.
Susan J. Schroeder
doaj +1 more source
Molecular basis of specific viral RNA recognition and 5′-end capping by the Chikungunya virus nsP1
Cell Reports, 2022 Summary: Many viruses encode RNA-modifying enzymes to edit the 5′ end of viral RNA to mimic the cellular mRNA for effective protein translation, genome replication, and evasion of the host defense mechanisms.
Kuo Zhang +7 more
doaj +1 more source
Neuroinflammation During RNA Viral Infections.
Annual Review of Immunology, 2019 Neurotropic RNA viruses continue to emerge and are increasingly linked to diseases of the central nervous system (CNS) despite viral clearance. Indeed, the overall mortality of viral encephalitis in immunocompetent individuals is low, suggesting ...
R. Klein +8 more
semanticscholar +1 more source
RNA Silencing and Plant Viral Diseases
Molecular Plant-Microbe Interactions, 2012 RNA silencing plays a critical role in plant resistance against viruses, with multiple silencing factors participating in antiviral defense. Both RNA and DNA viruses are targeted by the small RNA-directed RNA degradation pathway, with DNA viruses being ...
Ming-Bo Wang +3 more
doaj +1 more source
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources