Results 31 to 40 of about 1,113,600 (301)
Viral suppressors: Combatting RNA silencing [PDF]
Nature Plants, 2017 [EN] Plants defend themselves from invading viruses using RNA silencing. However, plant viruses try to spoil this defensive mechanism by expressing one or more proteins that act as RNA silencing suppressors. One such protein spoils plant defence by transporting the silencing signal into the peroxisomes to avoid its systemic spread.
openaire +5 more sources
Sequence organization of feline leukemis virus DNA in infected cells [PDF]
, 1980 A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W. +3 more
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Neuroinflammation During RNA Viral Infections [PDF]
Annual Review of Immunology, 2019 Neurotropic RNA viruses continue to emerge and are increasingly linked to diseases of the central nervous system (CNS) despite viral clearance. Indeed, the overall mortality of viral encephalitis in immunocompetent individuals is low, suggesting efficient mechanisms of virologic control within the CNS.
Robyn S, Klein +8 more
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Small Molecules Targeting Viral RNA
International Journal of Molecular Sciences, 2023 The majority of antivirals available target viral proteins; however, RNA is emerging as a new and promising antiviral target due to the presence of highly structured RNA in viral genomes fundamental for their replication cycle. Here, we discuss methods for the identification of RNA-targeting compounds, starting from the determination of RNA structures ...
Gregory Mathez, Valeria Cagno
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Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71
Viruses, 2019 The double-stranded RNA-binding protein Staufen1 (Stau1) has multiple functions during RNA virus infection. In this study, we investigated the role of Stau1 in viral translation by using a combination of enterovirus 71 (EV-A71) infection, RNA reporter ...
Young-Mao Chen +5 more
doaj +1 more source
Roles of the linker region of RNA helicase A in HIV-1 RNA metabolism. [PDF]
PLoS ONE, 2013 RNA helicase A (RHA) promotes multiple steps in HIV-1 production including transcription and translation of viral RNA, annealing of primer tRNA(Lys3) to viral RNA, and elevating the ratio of unspliced to spliced viral RNA.
Li Xing +3 more
doaj +1 more source
Genome organization and interaction with capsid protein in a multipartite RNA virus. [PDF]
, 2020 We report the asymmetric reconstruction of the single-stranded RNA (ssRNA) content in one of the three otherwise identical virions of a multipartite RNA virus, brome mosaic virus (BMV).
Beren, Christian +7 more
core
The effect of RNA stiffness on the self-assembly of virus particles [PDF]
, 2017 Under many in vitro conditions, some small viruses spontaneously encapsidate a single stranded (ss) RNA into a protein shell called the capsid. While viral RNAs are found to be compact and highly branched because of long distance base-pairing between ...
Erdemci-Tandogan, Gonca +3 more
core +3 more sources
Viral escape from antisense RNA [PDF]
Molecular Microbiology, 1998 RNA coliphage SP was propagated for several generations on a host expressing an inhibitory antisense RNA complementary to bases 31–270 of the positive‐stranded genome. Phages evolved that escaped inhibition. Typically, these escape mutants contained 3–4 base substitutions, but different sequences were observed among different isolates.
J J, Bull +3 more
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All About the RNA: Interferon-Stimulated Genes That Interfere With Viral RNA Processes
Frontiers in Immunology, 2020 Interferon (IFN) signaling induces the expression of a wide array of genes, collectively referred to as IFN-stimulated genes (ISGs) that generally function to inhibit viral replication.
Emily Yang +3 more
doaj +1 more source