Results 61 to 70 of about 2,788,248 (339)

Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71

Viruses, 2019
The double-stranded RNA-binding protein Staufen1 (Stau1) has multiple functions during RNA virus infection. In this study, we investigated the role of Stau1 in viral translation by using a combination of enterovirus 71 (EV-A71) infection, RNA reporter ...
Young-Mao Chen, Bo-Ting Ou, Chao-Ying Chen, Han-Hsiang Chan, Chih-Jung Chen, Robert YL Wang   +5 more
doaj   +1 more source

Nucleotide sequence and genomic organization of an ophiovirus associated with lettuce big-vein disease [PDF]

, 2002
The complete nucleotide sequence of an ophiovirus associated with lettuce big-vein disease has been elucidated. The genome consisted of four RNA molecules of approximately 7ò8, 1ò7, 1ò5 and 1ò4 kb.
Dullemans, A.M., Heuvel, J.F.J.M., van den, Verbeek, M., Wilk, F., van der   +3 more
core   +2 more sources

Replicon RNA Viral Vectors as Vaccines

Vaccines, 2016
Single-stranded RNA viruses of both positive and negative polarity have been used as vectors for vaccine development. In this context, alphaviruses, flaviviruses, measles virus and rhabdoviruses have been engineered for expression of surface protein ...
K. Lundstrom
semanticscholar   +1 more source

Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication

mBio, 2021
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an ongoing global public crisis. Although viral RNA modification has been reported based on the transcriptome architecture, the types and ...
Xueyan Zhang, Haojie Hao, Li Ma, Yecheng Zhang, Xiao Hu, Zhen Chen, Di Liu, Jianhui Yuan, Zhangli Hu, Wuxiang Guan   +9 more
doaj   +1 more source

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W., Davidson, Norman, Mullins, James I., Nicolson, Margery O.   +3 more
core   +1 more source

The Bacterial Symbiont Wolbachia Induces Resistance to RNA Viral Infections in Drosophila melanogaster

PLoS Biology, 2008
Wolbachia are vertically transmitted, obligatory intracellular bacteria that infect a great number of species of arthropods and nematodes. In insects, they are mainly known for disrupting the reproductive biology of their hosts in order to increase their
Luís Teixeira, Álvaro G A Ferreira, M. Ashburner   +2 more
semanticscholar   +1 more source

RNA-based viral vectors

Expert Review of Vaccines, 2014
The advent of reverse genetic approaches to manipulate the genomes of both positive (+) and negative (-) sense RNA viruses allowed researchers to harness these genomes for basic research. Manipulation of positive sense RNA virus genomes occurred first largely because infectious RNA could be transcribed directly from cDNA versions of the RNA genomes ...
Mark A, Mogler, Kurt I, Kamrud
openaire   +2 more sources

Discontinuous template switching generates coronavirus subgenomic RNAs from the 3ʹ viral genome end by 5ʹ to 3ʹ transcription

Journal of Virology
In coronavirus (CoV)-infected cells, several structural and accessory proteins are synthesized from subgenome RNAs (sgRNA) containing a common genomic 5ʹ-leader followed by a given open reading frame (ORF).
Ayslan Castro Brant, Zhe Hu, Angelika Zelma Chen, Vladimir Majerciak, Jonathan Yewdell, Zhi-Ming Zheng   +5 more
doaj   +1 more source

Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding

Cell Discovery, 2022
Little is known regarding why a subset of COVID-19 patients exhibited prolonged positivity of SARS-CoV-2 infection. Here, we found that patients with long viral RNA course (LC) exhibited prolonged high-level IgG antibodies and higher regulatory T (Treg ...
Xiaohua Tang, Rui Sun, Weigang Ge, Tingting Mao, Liujia Qian, Chongquan Huang, Zhouyang Kang, Qi Xiao, Meng Luo, Qiushi Zhang, Sainan Li, Hao Chen, Wei Liu, Bingjie Wang, Shufei Li, Xiaoling Lin, Xueqin Xu, Huanzheng Li, Lianpeng Wu, Jianyi Dai, Huanhuan Gao, Lu Li, Tian Lu, Xiao Liang, Xue Cai, Guan Ruan, Fei Xu, Yan Li, Yi Zhu, Ziqing Kong, Jianping Huang, Tiannan Guo   +31 more
doaj   +1 more source

Viral RNA export

Chemistry & Biology, 1997
Viruses can express intron-containing and intronless mRNAs, which are exported by alternative pathways. The study of the nuclear export of these unconventional mRNAs can provide key insights into the normal process of nuclear export and the alternative pathways provide an attractive target for the development of specific antiviral therapies.
openaire   +2 more sources