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Data of protein-RNA binding sites
Data in Brief, 2017 Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA ...
Wook Lee +3 more
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The compendium of Arabidopsis thaliana GLYCINE-RICH RNA-BINDING PROTEIN 8 in vivo targets determined by iCLIP [PDF]
Scientific DataRNA-binding proteins impact RNA processing including splicing, translation and RNA decay to dictate the fate of RNAs. Thus, insights into RNA-protein interactions in the cell provide insights into regulatory networks regulating gene expression at the ...
Katja Meyer +3 more
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The role of disorder in RNA binding affinity and specificity [PDF]
Open Biology, 2020 Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
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The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?
Frontiers in Oncology, 2021 The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li +6 more
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WormBook, 2006 The C. elegans genome encodes many RNA-binding proteins (RBPs) with diverse functions in development, indicative of extensive layers of post-transcriptional control of RNA metabolism. A number of C. elegans RBPs have been identified by forward or reverse genetics. They tend to display tissue-specific mutant phenotypes, which underscore their functional
Lee, Min'Ho, Schedl, Tim
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Helical defects in microRNA influence protein binding by TAR RNA binding protein. [PDF]
PLoS ONE, 2015 MicroRNAs (miRNAs) are critical post-transcriptional regulators of gene expression. Their precursors have a globally A-form helical geometry, which prevents most proteins from identifying their nucleotide sequence. This suggests the hypothesis that local
Roderico Acevedo +3 more
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Research progress of RNA binding motif protein family-mediated alternative splicing in cardiomyopathy [PDF]
Jichu yixue yu linchuang, 2022 RNA binding motif protein (RBM) is a type of RNA binding protein, which contains RNA recognition motif, RNA binding motif and ribo-nucleo-protein motif.
LIU Shu, DING Hong, ZHAO Ke-xin, BAI Feng, ZHANG Xiao-wei
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RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues
Frontiers in Cardiovascular Medicine, 2021 Background: Pathological tissue remodeling such as fibrosis is developed in various cardiac diseases. As one of cardiac activated-myofibroblast protein markers, CKAP4 may be involved in this process and the mechanisms have not been explored.Methods: We ...
Hong Zhu +7 more
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Genome Biology, 2022 Background Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale.
Klara Kuret +4 more
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Computational evolution of an RNA-binding protein towards enhanced oxidized-RNA binding
Computational and Structural Biotechnology Journal, 2020 The oxidation of RNA has been implicated in the development of many diseases. Among the four ribonucleotides, guanosine is the most susceptible to oxidation, resulting in the formation of 8-oxo-7,8-dihydroguanosine (8-oxoG). Despite the limited knowledge
Juan C. Gonzalez-Rivera +9 more
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