Results 1 to 10 of about 2,365,116 (344)
RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues [PDF]
Frontiers in Cardiovascular Medicine, 2021 Background: Pathological tissue remodeling such as fibrosis is developed in various cardiac diseases. As one of cardiac activated-myofibroblast protein markers, CKAP4 may be involved in this process and the mechanisms have not been explored.Methods: We ...
Hong Zhu +7 more
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Ataxin-2: a powerful RNA-binding protein [PDF]
Discover OncologyAtaxin-2 (ATXN2) was originally discovered in the context of spinocerebellar ataxia type 2 (SCA2), but it has become a key player in various neurodegenerative diseases.
Lulu Li +5 more
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The role of disorder in RNA binding affinity and specificity [PDF]
Open Biology, 2020 Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
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Research progress of RNA binding motif protein family-mediated alternative splicing in cardiomyopathy [PDF]
Jichu yixue yu linchuang, 2022 RNA binding motif protein (RBM) is a type of RNA binding protein, which contains RNA recognition motif, RNA binding motif and ribo-nucleo-protein motif.
LIU Shu, DING Hong, ZHAO Ke-xin, BAI Feng, ZHANG Xiao-wei
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RNA binding protein HuR protects against NAFLD by suppressing long noncoding RNA H19 expression
Cell & Bioscience, 2022 Background NAFLD has become the most common chronic liver disease worldwide. Human antigen R (HuR), an RNA-binding protein, is an important post-transcriptional regulator. HuR has been reported as a key player in regulating lipid homeostasis in the liver
Yanyan Wang +16 more
semanticscholar +1 more source
The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?
Frontiers in Oncology, 2021 The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li +6 more
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LC3B is an RNA-binding protein to trigger rapid mRNA degradation during autophagy
Nature Communications, 2022 LC3/ATG8 has long been appreciated to play a central role in autophagy, by which a variety of cytoplasmic materials are delivered to lysosomes and eventually degraded. However, information on the molecular functions of LC3 in RNA biology is very limited.
H. Hwang +5 more
semanticscholar +1 more source
Helical defects in microRNA influence protein binding by TAR RNA binding protein. [PDF]
PLoS ONE, 2015 MicroRNAs (miRNAs) are critical post-transcriptional regulators of gene expression. Their precursors have a globally A-form helical geometry, which prevents most proteins from identifying their nucleotide sequence. This suggests the hypothesis that local
Roderico Acevedo +3 more
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Genome Biology, 2022 Background Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale.
Klara Kuret +4 more
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Classifying RNA-binding proteins based on electrostatic properties. [PDF]
PLoS Computational Biology, 2008 Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
Shula Shazman, Yael Mandel-Gutfreund
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