Results 11 to 20 of about 1,877,035 (363)
Predicting RNA-binding residues from evolutionary information and sequence conservation [PDF]
BMC Genomics, 2010 Background RNA-binding proteins (RBPs) play crucial roles in post-transcriptional control of RNA. RBPs are designed to efficiently recognize specific RNA sequences after it is derived from the DNA sequence. To satisfy diverse functional requirements, RNA
Huang Chun-Chin +3 more
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Classifying RNA-binding proteins based on electrostatic properties. [PDF]
PLoS Computational Biology, 2008 Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
Shula Shazman, Yael Mandel-Gutfreund
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Chemoproteomic capture of RNA binding activity in living cells
Nature Communications, 2023 Proteomic methods for RNA interactome capture (RIC) rely principally on crosslinking native or labeled cellular RNA to enrich and investigate RNA-binding protein (RBP) composition and function in cells.
Andrew J. Heindel +10 more
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Protein-RNA interactions: a structural analysis [PDF]
, 2001 A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Berman, HM +4 more
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Possible Involvement of the Phloem Lectin in Long-Distance Viroid Movement
Molecular Plant-Microbe Interactions, 2001 Incubation with cucumber phloem exudate in vitro results in a dramatic decrease in the electrophoretic mobility of Hop stunt viroid. UV cross-linking and a combination of size exclusion and ion exchange chromatography indicate that this phenomenon ...
R. A. Owens, M. Blackburn, B. Ding
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Molecular principles underlying dual RNA specificity in the Drosophila SNF protein [PDF]
, 2018 The first RNA recognition motif of the Drosophila SNF protein is an example of an RNA binding protein with multi-specificity. It binds different RNA hairpin loops in spliceosomal U1 or U2 small nuclear RNAs, and only in the latter case requires the ...
DeKoster, Gregory T +4 more
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RNA binding proteins in osteoarthritis
Frontiers in Cell and Developmental Biology, 2022 Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder. Its progression is characterized by aberrant expression of genes involved in inflammation, proliferation, and metabolism of chondrocytes ...
Qian Yi +9 more
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Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera [PDF]
, 2013 DEAD box helicases catalyze the ATP-dependent destabilization of RNA duplexes. Whereas duplex separation is mediated by the helicase core shared by all members of the family, flanking domains often contribute to binding of the RNA substrate.
Klostermeier, Dagmar +5 more
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Crimean-Congo hemorrhagic fever virus nucleocapsid protein has dual RNA binding modes. [PDF]
PLoS ONE, 2017 Crimean Congo hemorrhagic fever, a zoonotic viral disease, has high mortality rate in humans. There is currently no vaccine for Crimean Congo hemorrhagic fever virus (CCHFV) and chemical interventions are limited.
Subbiah Jeeva +4 more
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Mechanism of RNA recognition by a Musashi RNA-binding protein
Current Research in Structural Biology, 2022 The Musashi RNA-binding proteins (RBPs) regulate translation of target mRNAs and maintenance of cell stemness and tumorigenesis. Musashi-1 (MSI1), long considered as an intestinal and neural stem cell marker, has been more recently found to be over ...
Jinan Wang +4 more
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