Results 21 to 30 of about 2,365,116 (344)
Crimean-Congo hemorrhagic fever virus nucleocapsid protein has dual RNA binding modes. [PDF]
PLoS ONE, 2017 Crimean Congo hemorrhagic fever, a zoonotic viral disease, has high mortality rate in humans. There is currently no vaccine for Crimean Congo hemorrhagic fever virus (CCHFV) and chemical interventions are limited.
Subbiah Jeeva +4 more
doaj +1 more source
Microbiology Spectrum, 2022 Proteomic profiling of RNA-binding proteins in Leishmania is currently limited to polyadenylated mRNA-binding proteins, leaving proteins that interact with nonadenylated RNAs, including noncoding RNAs and pre-mRNAs, unidentified.
Karunakaran Kalesh +5 more
doaj +1 more source
RNA-binding proteins in tumor progression [PDF]
Journal of Hematology & Oncology, 2020 AbstractRNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome through post-transcriptionally controlling the processing and transportation of RNA, including regulating RNA splicing, polyadenylation, mRNA stability, mRNA localization, and ...
Hai Qin +6 more
openaire +4 more sources
Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)
Nature Methods, 2016 As RNA-binding proteins (RBPs) play essential roles in cellular physiology by interacting with target RNA molecules, binding site identification by UV crosslinking and immunoprecipitation (CLIP) of ribonucleoprotein complexes is critical to understanding
Eric L. Van Nostrand +13 more
semanticscholar +1 more source
PredPRBA: Prediction of Protein-RNA Binding Affinity Using Gradient Boosted Regression Trees
Frontiers in Genetics, 2019 Protein-RNA interactions play essential roles in many biological aspects. Quantifying the binding affinity of protein-RNA complexes is helpful to the understanding of protein-RNA recognition mechanisms and identification of strong binding partners.
Lei Deng, Lei Deng, Wenyi Yang, Hui Liu
doaj +1 more source
The kinetic landscape of an RNA binding protein in cells
bioRxiv, 2020 Gene expression in higher eukaryotic cells orchestrates interactions between thousands of RNA-binding proteins (RBPs) and tens of thousands of RNAs 1 .
D. Sharma +6 more
semanticscholar +1 more source
Regulation of Pluripotency by RNA Binding Proteins [PDF]
Cell Stem Cell, 2014 Establishment, maintenance, and exit from pluripotency require precise coordination of a cell's molecular machinery. Substantial headway has been made in deciphering many aspects of this elaborate system, particularly with respect to epigenetics, transcription, and noncoding RNAs. Less attention has been paid to posttranscriptional regulatory processes
Ye, Julia, Blelloch, Robert
openaire +4 more sources
Role of the RNA-binding protein La in cancer pathobiology
RNA Biology, 2020 RNA-binding proteins are important regulators of RNA metabolism and are of critical importance in all steps of the gene expression cascade. The role of aberrantly expressed RBPs in human disease is an exciting research field and the potential application
G. Sommer, T. Heise
semanticscholar +1 more source
RNA-binding protein signaling in adult neurogenesis
Frontiers in Cell and Developmental Biology, 2022 The process of neurogenesis in the brain, including cell proliferation, differentiation, survival, and maturation, results in the formation of new functional neurons.
Jackie Ngai-Man Chan +6 more
doaj +1 more source
Autophagy, 2018 Ferroptosis is a recently recognized form of regulated cell death that is characterized by lipid peroxidation. However, the molecular mechanisms regulating ferroptosis are largely unknown.
Zili Zhang +7 more
semanticscholar +1 more source