Results 101 to 110 of about 5,120 (129)

Insights into the function and structure of the R2TP (RUVBL1-RUVBL2-RPAP3-PIH1D1)chaperone complex. [PDF]

Cell Stress Chaperones
Mohamed M, Wu R, Houry WA.
europepmc   +1 more source

Discovery of a First-in-Class Murine Double Minute 2-Recruiting Positive Transcription Elongation Factor B PROTAC Degrader With Selective Antitumor Activity. [PDF]

MedComm (2020)
Guan X, Xie L, Guo H, Ma L, Zhou J, Luo L, Yang H, Wu Y, Liu J, Wang Y, Huang X, Liu J, Zhang Y, Chen W, Chen Y, Xu L, Han X.   +16 more
europepmc   +1 more source

Molecular regulation of PGC-1α: from protein-protein interactions and post-translational modifications to pharmacological modulation. [PDF]

J Mol Med (Berl)
Rios WQ, Silva CM, Ferreira R, Gomes JRB.   +3 more
europepmc   +1 more source

Fulfilling multiple roles in PROTAC design: The emerging potential of oligonucleotides. [PDF]

Eur J Med Chem
Rodrigues DA, Pires GS, Roy U, Conway E, de Sena Murteira Pinheiro P.   +4 more
europepmc   +1 more source

Ewing sarcoma depends on C4orf48/NICOL, a NELL2 cofactor regulated by Hippo signaling. [PDF]

Cell Signal
Jayabal P, Ma X, Chen Y, Yuan Y, Shiio Y.   +4 more
europepmc   +1 more source

High 4E-BP1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing sarcoma. [PDF]

J Clin Invest
Funk CM, Ehlers AC, Orth MF, Aljakouch K, Li J, Hölting TL, Will R, Geyer FH, Ceranski AK, Willis F, Vinca E, Ohmura S, Imle R, Siebenlist J, Yershova A, Knott MM, Zahnow F, Sastre A, Alonso J, Sahm F, Peterziel H, Loboda A, Schneider M, Banito A, Leprivier G, Hartmann W, Dirksen U, Witt O, Oehme I, Pfister SM, Romero-Pérez L, Krijgsveld J, Cidre-Aranaz F, Grünewald TG, Musa J.   +34 more
europepmc   +1 more source

Unfolded Protein Response as a Therapeutic Target: 4-(Heptyloxy)phenol Induces Programmed Cell Death in Ewing Sarcoma. [PDF]

Mol Cancer Ther
Zhang N, Perez M, Jenkins GN, Horton TM, Gilbertson SR, Pati D.   +5 more
europepmc   +1 more source

A validated panel of commercial antibodies for reliable detection of FET proteins

Tacconelli S, Odemwingie L, Reber S, Pancrazio SD, Zoller TI, Biasetti L, Troakes C, Ruepp M, Vance C.   +8 more
europepmc   +1 more source

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma. [PDF]

J Cell Physiol
Rahimizadeh P, Miallot R, De Bellis C, Jolivet P, Przybyl J.   +4 more
europepmc   +1 more source

EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism. [PDF]

Oncogene
Olmedo-Pelayo J, Granado-Calle E, Delgado-Bellido D, Lobo-Selma L, Jordan-Perez C, Monteiro-Amaral AT, Ehlers AC, Ohmura S, Garcia-Dominguez DJ, Mackintosh C, Carcaboso AM, Alonso J, Machado I, Llombart-Bosch A, Scotlandi K, Grünewald TGP, Gomez-Herreros F, de Alava E.   +17 more
europepmc   +1 more source