Results 111 to 120 of about 5,120 (129)

New cell lines expanding the diversity of Ewing sarcoma models. [PDF]

Int J Cancer
Kerkhoff M, Schaefer C, Dirks WG, Krzeciesa D, Bretschneider M, Plaumann PR, Guder WK, Streitbürger A, Herter S, Peterziel H, Oehme I, Zahnow F, Grünewald TGP, Dirksen U.   +13 more
europepmc   +1 more source

Advantages and Challenges of G‑Quadruplexes in Regulating Alternative Splicing. [PDF]

JACS Au
Huang H, Zhou X.
europepmc   +1 more source

Abstract 204: Molecular function of the RNA binding protein EWS in RNA processing

Cancer Research, 2012
Abstract The Ewing Sarcoma (EWS) protein is a member of the FET family of RNA-binding proteins and is involved in chromosomal translocations that generate oncogenic fusion genes found in a variety of sarcomas. EWS has been recently reported to be involved in regulating transcription, pre-mRNA processing, translation and DNA repair ...
Bethsaida I. Nieves, Shuang Niu, Dedeepya Vaka, Julia Salzman, Patrick Brown, Alejandro I. Sweet-Cordero   +5 more
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RNA-binding protein EWS, a novel modulator of LTβR signaling

The Journal of Immunology, 2019
Abstract Efficient immune responses depend on signaling networks coordinated by dynamic protein-protein interactions. Adaptor proteins, like TRAF3, participates in distinct signaling pathways critical for immune development and host defense.
Richard Virgen-Slane, Ricardo G Correa, Parham Ramezani-Rad, Alexandre Rosa-Campos, Jun Li, Carl F Ware   +5 more
openaire   +1 more source

Elucidating the physiological function of the RNA binding protein EWS and its role in post-transcriptional gene regulation

, 2015
Duggimpudi, Sujitha smruthy
openaire   +2 more sources

The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains.

Oncogene, 1994
The EWS gene, which maps to band q12 of human chromosome 22, is involved in a wide variety of human solid tumors including Ewing sarcoma, related primitive neuroectodermal tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors. In these tumors, the EWS is fused to genes encoding transcriptional activators/repressors, like Fli-
T, Ohno, M, Ouchida, L, Lee, Z, Gatalica, V N, Rao, E S, Reddy   +5 more
openaire   +1 more source

Structural Analysis of RNA-Binding Protein EWSR1 Involved in Ewing’s Sarcoma Through Domain Assembly and Conformational Molecular Dynamics Studies

2023
Saba Shahzadi, Mubashir Hassan, Andrzej Kloczkowski   +2 more
openaire   +1 more source

Biochemical and biophysical characterization of the nucleic acid binding properties of the RNA/DNA binding protein EWS

Biopolymers, 2023
Emily E Selig, Matthew R White, Rachell E Booth   +2 more
exaly  

A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells

Journal of Biological Chemistry, 2023
Benjamin M Greulich, Nicholas F Downing, Taylor R Nicholas   +2 more
exaly  

O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics

Journal of the American Chemical Society, 2021
Michael L Nosella, Iva Pritišanac, P Andrew Chong   +2 more
exaly