Results 11 to 20 of about 2,765,005 (400)
WormBook, 2006 The C. elegans genome encodes many RNA-binding proteins (RBPs) with diverse functions in development, indicative of extensive layers of post-transcriptional control of RNA metabolism. A number of C. elegans RBPs have been identified by forward or reverse
Lee, Min\u27Ho, Schedl, Tim
core +7 more sources
Guardian of Genetic Messenger-RNA-Binding Proteins [PDF]
Biomolecules, 2016 RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express
Antje Anji, Meena Kumari
doaj +4 more sources
Identification of RNA-binding Proteins [PDF]
Bio-Protocol, 2016 This protocol describes the extraction of RNA-binding proteins (RBPs) from cell lysates. In order to pull down target RBPs, 5-bromo-UTP (BrUTP)-incorporated RNA probes are used, which are generated by in vitro transcription.
Kazuya Masuda, Tadamitsu Kishimoto
doaj +2 more sources
RNA-binding proteins in bacteria [PDF]
Nature Reviews Microbiology, 2018 RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the way for molecular studies of RNA-protein interactions.
Erik Holmqvist, J. Vogel
semanticscholar +5 more sources
The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid. [PDF]
PLoS Pathogens, 2016 The APOBEC3 (A3) cytidine deaminases are antiretroviral proteins, whose targets include human immunodeficiency virus type-1 (HIV-1). Their incorporation into viral particles is critical for antiviral activity and is driven by interactions with the RNA ...
Ashley York +3 more
doaj +5 more sources
Predicting RNA-binding residues from evolutionary information and sequence conservation [PDF]
BMC Genomics, 2010 Background RNA-binding proteins (RBPs) play crucial roles in post-transcriptional control of RNA. RBPs are designed to efficiently recognize specific RNA sequences after it is derived from the DNA sequence. To satisfy diverse functional requirements, RNA
Huang Chun-Chin +3 more
doaj +4 more sources
Editorial: RNA binding proteins in neuroscience
Frontiers in Molecular Neuroscience, 2023 Anca F. Savulescu, Epaminondas Doxakis
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RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues [PDF]
Frontiers in Cardiovascular Medicine, 2021 Background: Pathological tissue remodeling such as fibrosis is developed in various cardiac diseases. As one of cardiac activated-myofibroblast protein markers, CKAP4 may be involved in this process and the mechanisms have not been explored.Methods: We assumed that CKAP4 held a role in the regulation of cardiac fibrotic remodeling as an RNA-binding ...
Hong Zhu +7 more
openaire +3 more sources
bioRxiv, 2022 Macromolecular phase separation is thought to be one of the processes that drives the formation of membraneless biomolecular condensates in cells. The dynamics of phase separation, especially at low endogenous concentrations found in cells, are thought ...
Mrityunjoy Kar +12 more
semanticscholar +1 more source
A large-scale binding and functional map of human RNA-binding proteins
Nature, 2020 Many proteins regulate the expression of genes by binding to specific regions encoded in the genome1. Here we introduce a new data set of RNA elements in the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the ...
Eric L. Van Nostrand +37 more
semanticscholar +1 more source