Results 21 to 30 of about 1,493,002 (262)
Identification of novel components of Trypanosoma brucei editosomes [PDF]
The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome proteins in Trypanosoma brucei.
Carmean, Nicole+6 more
core +2 more sources
rMAPS: RNA map analysis and plotting server for alternative exon regulation. [PDF]
RNA-binding proteins (RBPs) play a critical role in the regulation of alternative splicing (AS), a prevalent mechanism for generating transcriptomic and proteomic diversity in eukaryotic cells.
Jung, Sungbo+4 more
core +2 more sources
The RNA binding specificity of human APOBEC3 proteins resembles that of HIV-1 nucleocapsid [PDF]
The APOBEC3 (A3) cytidine deaminases are antiretroviral proteins, whose targets include human immunodeficiency virus type-1 (HIV-1). Their incorporation into viral particles is critical for antiviral activity and is driven by interactions with the RNA ...
Bieniasz, Paul D+3 more
core +4 more sources
Chloroplast RNA-binding proteins [PDF]
Chloroplast gene expression is regulated by nucleus-encoded factors, which mainly act at the post-transcriptional level. Plastid RNA-binding proteins (RBPs) represent good candidates for mediating these functions. The picture emerging from recent analyses is that of a great number of differentially regulated RBPs, which are organized in distinct ...
openaire +3 more sources
RNA Binding Proteins in the miRNA Pathway [PDF]
microRNAs (miRNAs) are short ~22 nucleotides (nt) ribonucleic acids which post-transcriptionally regulate gene expression. miRNAs are key regulators of all cellular processes, and the correct expression of miRNAs in an organism is crucial for proper development and cellular function. As a result, the miRNA biogenesis pathway is highly regulated.
Gyorgy Hutvagner+2 more
openaire +3 more sources
Secondary structure prediction for RNA binding domain in RNP proteins identifies βαβ as the main structural motif [PDF]
In eukaryotic cells transcript processing is strictly dependent upon binding of specific proteins. Nuclear RNA binding proteins share a common domain, which is involved in RNA binding.
Di Cesare, G.+3 more
core +1 more source
RNA-Binding Proteins in Plant Immunity [PDF]
Plant defence responses against pathogen infection are crucial to plant survival. The high degree of regulation of plant immunity occurs both transcriptionally and posttranscriptionally. Once transcribed, target gene RNA must be processed prior to translation. This includes polyadenylation,5′capping, editing, splicing, and mRNA export.
Shuai Huang, Virginia Woloshen, Xin Li
openaire +2 more sources
PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs [PDF]
A large number of RNA binding proteins (RBPs) and miRNAs bind to the 3′ untranslated regions of mRNA, but methods to dissect their function and interactions are lacking.
Chaudhari, Hemangi G+3 more
core +3 more sources
Advances in the characterization of RNA‐binding proteins
From transcription, to transport, storage, and translation, RNA depends on association with different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and protein mass‐spectrometry have started to unveil genome‐wide interactions of RBPs but many aspects still remain out of sight.
Domenica Marchese+5 more
openaire +5 more sources
RNA-binding proteins in neurological diseases [PDF]
Emerging studies support that RNA-binding proteins (RBPs) play critical roles in human biology and pathogenesis. RBPs are essential players in RNA processing and metabolism, including pre-mRNA splicing, polyadenylation, transport, surveillance, mRNA localization, mRNA stability control, translational control and editing of various types of RNAs ...
Jianghong Liu+5 more
openaire +4 more sources