Results 31 to 40 of about 1,493,002 (262)

Saturation mutagenesis reveals manifold determinants of exon definition. [PDF]

, 2017
To illuminate the extent and roles of exonic sequences in the splicing of human RNA transcripts, we conducted saturation mutagenesis of a 51-nt internal exon in a three-exon minigene.
Anquetil, Vincent, Arias, Mauricio A., Chasin, Lawrence A., Ju, Jingyue, Kalachikov, Sergey, Ke, Shengdong, Maity, Alisha, Russo, James J, Yang, Anthony, Zamalloa, Jorge Rojas   +9 more
core   +2 more sources

FLASH: ultra-fast protocol to identify RNA-protein interactions in cells

, 2019
Determination of the in vivo binding sites of RNA-binding proteins (RBPs) is paramount to understanding their function and how they affect different aspects of gene regulation.
Akhtar, A., Aktas, T., Backofen, R., Ilik, I., Maticzka, D.   +4 more
core   +1 more source

Classifying RNA-Binding Proteins Based on Electrostatic Properties [PDF]

, 2008
Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
A Andreeva, A Lingel, A Szilagyi, AG Murzin, BL Staker, BM Lunde, C Maris, CE Felder, CH Ding, CZ Cai, D Tworowski, DE Brodersen, DE Draper, EW Stawiski, F Bono, F Cazals, G Bejerano, G Nimrod, GB Robb, HP Shanahan, I Friedberg, I Guyon, IB Kuznetsov, J Cavarelli, JD Keene, JJ Ellis, JR Bock, JS Mattick, JS Parker, L Corsini, L ElAntak, L Wang, LY Han, M Ruff, M Terribilini, M Terribilini, N Bhardwaj, NM Luscombe, P Sampath, P Sanchez-Diaz, PM Dehe, R Karchin, RN De Guzman, S Ahmad, S Ahmad, S Jones, S Jones, S Jones, S Ramaswamy, S Shazman, Shula Shazman, T Burckin, U Hobohm, Uwe Ohler, X Yang, X Yu, Y Chen, Y Hargous, Y Mandel-Gutfreund, Y Nakamura, Y Xing, Yael Mandel-Gutfreund, YC Chen, YD Cai, YD Cai, YD Cai   +65 more
core   +4 more sources

Trim25 is an RNA-specific activator of Lin28a/TuT4-mediated uridylation [PDF]

, 2014
SummaryRNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4 ...
Ascano, Baltz, Castello, Chang, Cho, Choudhury, Choudhury, Gack, Glisovic, Guil, Hafner, Hagan, Havens, Hentze, Heo, Heo, Inn, Kwon, Lee, Lehrbach, Lightfoot, Loughlin, Michlewski, Michlewski, Michlewski, Michlewski, Milek, Nam, Nowak, Nowak, Pandit, Piskounova, Ray, Rybak, Shyh-Chang, Shyh-Chang, Singh, Thornton, Towbin, Urbach, Ustianenko, Van Wynsberghe, Versteeg, Viswanathan, Wilbert, Yang   +45 more
core   +3 more sources

Data of protein-RNA binding sites

Data in Brief, 2017
Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA-binding sites in protein sequences. The problem of predicting protein-binding sites in RNA has received
Byungkyu Park, Wook Lee, Kyungsook Han, Daesik Choi   +3 more
openaire   +4 more sources

RNA Binding Proteins and Genome Integrity [PDF]

International Journal of Molecular Sciences, 2017
Genome integrity can be threatened by various endogenous or exogenous events. To counteract these stressors, the DNA damage response network contributes to the prevention and/or repair of genomic DNA damage and serves an essential function in cellular survival. DNA binding proteins are involved in this network.
Nishida, Kensei, Kuwano, Yuki, Nishikawa, Tatsuya, Masuda, Kiyoshi, Rokutan, Kazuhito   +4 more
openaire   +2 more sources

The increasing diversity of functions attributed to the SAFB family of RNA/DNA binding proteins [PDF]

, 2016
RNA-binding proteins play a central role in cellular metabolism by orchestrating the complex interactions of coding, structural and regulatory RNA species.
Idris, Jalilah, Lee, Youn Bok, Norman, Michael, Rivers, Caroline, Uney, James   +4 more
core   +2 more sources

Novel RNA-binding properties of the MTG chromatin regulatory proteins [PDF]

, 2008
Background: The myeloid translocation gene (MTG) proteins are non-DNA-binding transcriptional regulators capable of interacting with chromatin modifying proteins. As a consequence of leukemia-associated chromosomal translocations, two of the MTG proteins,
Hoogeveen, Andre T, Rossetti, Stefano, Sacchi, Nicoletta, van Unen, Leontine   +3 more
core   +4 more sources

An in Vitro Technique to Identify the RNA Binding-Site Sequences for RNA-Binding Proteins [PDF]

BioTechniques, 2017
RNA-protein interactions play a major role in gene regulation. Although many techniques to analyze RNA-protein interactions have been developed, noteworthy challenges such as determining the RNA sequences that bind RNA-binding proteins (RBPs) remain unsolved.
Sunkyung Choi, Kyoon Eon Kim, Chungoo Park, Kee K. Kim   +3 more
openaire   +4 more sources

Filling a GAP(DH) in Asymmetric Viral RNA Synthesis [PDF]

, 2008
SummaryHost proteins, such as RNA-binding proteins, are involved in most steps of replication by positive-strand RNA viruses, including Tomato bushy stunt virus (TBSV). In this issue of Cell Host & Microbe, Wang and Nagy report that efficient replication
Ahlquist, Paul, Wang, Xiaofeng
core   +1 more source