Results 11 to 20 of about 1,122,786 (246)

Classifying RNA-binding proteins based on electrostatic properties. [PDF]

open access: yesPLoS Computational Biology, 2008
Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
Shula Shazman, Yael Mandel-Gutfreund
doaj   +1 more source

RNA-binding proteins in tumor progression

open access: yesJournal of Hematology & Oncology, 2020
RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome through post-transcriptionally controlling the processing and transportation of RNA ...
Hai Qin   +6 more
doaj   +1 more source

RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific

open access: yesScientific Reports, 2023
Thousands of RNA-binding proteins (RBPs) crosslink to cellular mRNA. Among these are numerous unconventional RBPs (ucRBPs)—proteins that associate with RNA but lack known RNA-binding domains (RBDs).
Debashish Ray   +17 more
doaj   +1 more source

Survey of the binding preferences of RNA-binding proteins to RNA editing events

open access: yesGenome Biology, 2022
Background Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional process related to a multitude of cellular and molecular activities.
Xiaolin Hu, Qin Zou, Li Yao, Xuerui Yang
doaj   +1 more source

The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?

open access: yesFrontiers in Oncology, 2021
The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li   +6 more
doaj   +1 more source

Identification of RNA-binding Proteins

open access: yesBio-Protocol, 2016
This protocol describes the extraction of RNA-binding proteins (RBPs) from cell lysates. In order to pull down target RBPs, 5-bromo-UTP (BrUTP)-incorporated RNA probes are used, which are generated by in vitro transcription.
Kazuya Masuda, Tadamitsu Kishimoto
doaj   +1 more source

γ-AApeptides bind to RNA by mimicking RNA-binding proteins [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2011
The interactions between proteins and RNAs are of vital importance for many cellular processes, including transcription and processing of RNA, translation, and viral infections. Here we report an γ-AApeptide that can mimic HIV-1 Tat protein and bind to TAR RNAs of HIV and BIV with nanomolar affinity, comparable to that of the RNA-binding fragment of ...
Youhong, Niu   +4 more
openaire   +2 more sources

Chloroplast RNA-binding proteins [PDF]

open access: yesCurrent Genetics, 2003
Chloroplast gene expression is regulated by nucleus-encoded factors, which mainly act at the post-transcriptional level. Plastid RNA-binding proteins (RBPs) represent good candidates for mediating these functions. The picture emerging from recent analyses is that of a great number of differentially regulated RBPs, which are organized in distinct ...
openaire   +2 more sources

Plant RNA binding proteins for control of RNA virus infection

open access: yesFrontiers in Physiology, 2013
Plant RNA viruses have effective strategies to infect host plants through either direct or indirect interactions with various host proteins, thus suppressing the host immune system.
Sung Un eHuh, Kyung-Hee ePaek
doaj   +1 more source

Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules

open access: yesBiomolecules, 2020
Spatiotemporal translational regulation plays a key role in determining cell fate and function. Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and long-term memory formation.
Rie Ohashi, Nobuyuki Shiina
doaj   +1 more source

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