Results 261 to 270 of about 2,133,969 (419)

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source

Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer. [PDF]

Sci Rep
Wang LY, Shi J, Wang MF, Liu YM, Guo HS, Wang JC, Jiang S, Liang JQ, Liao XH, Chen SY.   +9 more
europepmc   +1 more source

A novel type of RNA editing occurs in the mitochondrial tRNAs of the centipede Lithobius forficatus

, 2000
Dennis V. Lavrov, Wesley M. Brown, Jeffrey L. Boore   +2 more
openalex   +1 more source

Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei [PDF]

, 2001
Michael T. McManus, Masako Shimamura, Jayleen Grams, Stephen L. Hajduk   +3 more
openalex   +1 more source

Engineered 3D Kidney Glomerular Microtissues to Model Podocyte‐Centric Diseases for the Validation of New Drug Targets

Advanced Healthcare Materials, EarlyView.
The study introduces innovative 3D microtissues that replicate the glomerular filtration barrier of the kidney, offering a novel platform for understanding podocytopathies. These microtissues simulate the glomerulus's structure and dynamics, allowing for the modeling of podocyte injuries and drug testing.
Sara Buttό, Solange Vidal, Xi Rui Zeng, Martin Rausch, Immihan Ceren Yasa, Magali P. Ferro   +5 more
wiley   +1 more source

3'UTR RNA editing driven by ADAR1 modulates MDM2 expression in breast cancer cells. [PDF]

Funct Integr Genomics
Almeric E, Karagozoglu D, Cicek M, Dioken DN, Tac HA, Cicek E, Kirim BA, Gurcuoglu I, Sezerman OU, Ozlu N, Erson-Bensan AE.   +10 more
europepmc   +1 more source

Chloroplast RNA Editing Required for Functional Acetyl-CoA Carboxylase in Plants [PDF]

, 2001
Yukiko Sasaki, Akiko Kozaki, Akira Ohmori, Hiro Iguchi, Yukio Nagano   +4 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Astrocytic RNA editing regulates the host immune response to alpha-synuclein. [PDF]

Sci Adv
D'Sa K, Choi ML, Wagen AZ, Setó-Salvia N, Kopach O, Evans JR, Rodrigues M, Lopez-Garcia P, Lachica J, Clarke BE, Singh J, Ghareeb A, Bayne J, Grant-Peters M, Garcia-Ruiz S, Chen Z, Rodriques S, Athauda D, Gustavsson EK, Gagliano Taliun SA, Toomey C, Reynolds RH, Young G, Strohbuecker S, Warner T, Rusakov DA, Patani R, Bryant C, Klenerman DA, Gandhi S, Ryten M.   +30 more
europepmc   +1 more source

Mutagenesis of Apobec-1 Complementation Factor Reveals Distinct Domains That Modulate RNA Binding, Protein-Protein Interaction with Apobec-1, and Complementation of C to U RNA-editing Activity [PDF]

, 2001
Valérie Blanc, Jeffrey O. Henderson, Susan Kennedy, Nicholas O. Davidson   +3 more
openalex   +1 more source