Results 21 to 30 of about 694,106 (294)

Genomic Identification of RNA Editing Through Integrating Omics Datasets and the Clinical Relevance in Hepatocellular Carcinoma

Frontiers in Oncology, 2020
RNA editing is a widespread post-transcriptional mechanism to introduce single nucleotide changes to RNA in human cancers. Here, we characterized the global RNA editing profiles of 373 hepatocellular carcinoma (HCC) and 50 adjacent normal liver samples ...
Juan Chen, Lu Wang, Fangbin Wang, Jian Liu, Jian Liu, Zhenyu Bai   +5 more
doaj   +1 more source

Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]

, 2012
Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor, Achim Schnaufer, Alatortsev, Ammerman, Aphasizheva, Aphasizheva, Bailey, Borst, Carnes, Carnes, Carnes, Cruz-Reyes, Cruz-Reyes, Deschamps, Ernst, Ernst, Etheridge, Fisk, Guo, Guo, Guo, Hashimi, Igo, Igo, Inoue, Jason Carnes, Jensen, Kao, Kenneth Stuart, Koslowsky, Koslowsky, Lukes, Mattiacio, Mattiacio, Melissa Lerch, Militello, Nathalie Acestor, Niemann, Panigrahi, Panigrahi, Panigrahi, Panigrahi, Panigrahi, Panigrahi, Piller, Rigaut, Ryan, Sabatini, Schnaufer, Schnaufer, Seiwert, Simpson, Stuart, Trotter, Weng, Wirtz, Worthey, Xuemin Guo, Zhang   +58 more
core   +1 more source

Activity-regulated RNA editing in select neuronal subfields in hippocampus [PDF]

, 2012
RNA editing by adensosine deaminases is a widespread mechanism to alter genetic information in metazoa. In addition to modifications in non-coding regions, editing contributes to diversification of protein function, in analogy to alternative splicing ...
Ales Balik, Altschul, Andrew C. Penn, Aruscavage, Bass, Birney, Bratt, Brorson, Coleman, Coleman, Daniel, Darty, Dawson, de la Mata, Feldmeyer, Feng, Fisahn, Gahwiler, Gainey, Gallo, Ge, Goodman, Greger, Greger, Greger, Gurevich, Hamada, Hideyama, Hideyama, Higuchi, Higuchi, Hoopengardner, Hundley, Ingo H. Greger, Jepson, Katoh, Kent, Lee, Lein, Li, Liu, Lomeli, Maas, Marcucci, Palladino, Paul, Peng, Peng, Penn, Penn, Penn, Pozo, Rosenthal, Rueter, Ryman, Sanjana, Schoft, Seeburg, Seeburg, Sommer, Sommer, Stefl, Stefl, Tariq, Toth, Traynelis, Turrigiano, Turrigiano, Valente, Venkatesh, Wang, Witter, Xie, Zsofia Nemoda   +73 more
core   +1 more source

Survey of the binding preferences of RNA-binding proteins to RNA editing events

Genome Biology, 2022
Background Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional process related to a multitude of cellular and molecular activities.
Xiaolin Hu, Qin Zou, Li Yao, Xuerui Yang
doaj   +1 more source

Genome-wide characterization of RNA editing highlights roles of high editing events of glutamatergic synapse during mouse retinal development

Computational and Structural Biotechnology Journal, 2022
Adenosine-to-inosine (A-to-I) RNA editing leads to functional change of neurotransmitter receptor which is essential for neurotransmission and normal neuronal development. As a highly accessible part of central nervous system, retina has been extensively
Chenghao Li, Xinrui Shi, Jiaying Yang, Ke Li, Lijun Dai, Yan Zhang, Meng Zhou, Jianzhong Su   +7 more
doaj   +1 more source

Universal RNA editing in a human liver at the fetal stage [PDF]

, 2012
It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, rRNA,
Chen, Huiping, Ingvarsson, Sigurður, Liu, Cong, Liu, Dong, Wang, Xiyin   +4 more
core   +1 more source

RNA Editing: An I for editing [PDF]

Current Biology, 1995
In vitro editing in mammalian nuclear extracts reveals adenosine-to-inosine conversions in glutamate receptor messenger RNAs.
openaire   +2 more sources

Canonical A-to-I and C-to-U RNA editing is enriched at 3'UTRs and microRNA target sites in multiple mouse tissues. [PDF]

PLoS ONE, 2012
RNA editing is a process that modifies RNA nucleotides and changes the efficiency and fidelity of the central dogma. Enzymes that catalyze RNA editing are required for life, and defects in RNA editing are associated with many diseases. Recent advances in
Tongjun Gu, Frank W Buaas, Allen K Simons, Cheryl L Ackert-Bicknell, Robert E Braun, Matthew A Hibbs   +5 more
doaj   +1 more source

Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections

Frontiers in Immunology, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Zhi-Yuan Wei, Zhi-Yuan Wei, Zhi-Yuan Wei, Zhi-Xin Wang, Zhi-Xin Wang, Zhi-Xin Wang, Jia-Huan Li, Jia-Huan Li, Jia-Huan Li, Yan-Shuo Wen, Yan-Shuo Wen, Yan-Shuo Wen, Di Gao, Di Gao, Di Gao, Shou-Yue Xia, Shou-Yue Xia, Shou-Yue Xia, Yu-Ning Li, Yu-Ning Li, Yu-Ning Li, Xu-Bin Pan, Xu-Bin Pan, Xu-Bin Pan, Yan-Shan Liu, Yun-Yun Jin, Yun-Yun Jin, Yun-Yun Jin, Jian-Huan Chen, Jian-Huan Chen, Jian-Huan Chen   +30 more
doaj   +1 more source

Evolution of substrate-specific gene expression and RNA editing in brown rot wood-decaying fungi. [PDF]

, 2019
Fungi that decay wood have characteristic associations with certain tree species, but the mechanistic bases for these associations are poorly understood.
Ahrendt, Steven, Blanchette, Robert A, Cullen, Daniel, Gaskell, Jill, Grigoriev, Igor V, Hibbett, David S, Master, Emma, Schilling, Jonathan S, Toapanta, Christina, Wu, Baojun, Zhang, Jiwei   +10 more
core   +1 more source