Results 231 to 240 of about 508,217 (335)

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

Disruption of <i>TcGNBP3</i> via RNA interference compromises antibacterial immunity in <i>Tribolium castaneum</i>. [PDF]

Virulence
Bi J, Li Q, Liu P, Li J, Gao R, Zhao T, Yuan X, Hao H, Wang Y, Li B.   +9 more
europepmc   +1 more source

DICER-ARGONAUTE2 Complex in Continuous Fluorogenic Assays of RNA Interference Enzymes

, 2015
M. Bernard, Leyu Wang, Souvenir D. Tachado   +2 more
openalex   +2 more sources

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Natural CCD2 Variants and RNA Interference for Boosting Crocin Biosynthesis in Tomato. [PDF]

Biology (Basel)
Moreno-Giménez E, Parreño E, Morote L, López Jiménez AJ, Martínez Fajardo C, Presa S, Rubio-Moraga Á, Granell A, Ahrazem O, Gómez-Gómez L.   +9 more
europepmc   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Targeting the proteasome subunit PSMB5 by RNA interference induces proteasome dysfunction and mortality in the Colorado potato beetle (Leptinotarsa decemlineata). [PDF]

Sci Rep
Graser L, Gordon ER, Jamison M, Talton W, Chen Y, Knorr E, Windfelder A, Narva K, Vilcinskas A.   +8 more
europepmc   +1 more source

Ornithine and Tryptophan Analogs as Efficient Polycations for Short Interference RNA Delivery to Tumor Cells

, 2010
Yusuke Sato, Hiroto Hatakeyama, Hideyoshi Harashima   +2 more
openalex   +2 more sources

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Teaching molecular genetics using <i>Paramecium</i> and RNA interference: research-based learning and project ownership. [PDF]

J Microbiol Biol Educ
Valentine MS, Johnson K, Veramendi MB, James C, Kozak J, Patwardhan A, Quartey R.   +6 more
europepmc   +1 more source