Results 181 to 190 of about 74,683 (214)

Molecular Adaptations and Sex‐Biased Regulatory Pathways in Multi‐Year Diapause of the Cabbage Beetle Colaphellus bowringi: A Duration‐Resolved Transcriptomic Analysis

Ecology and Evolution, Volume 16, Issue 11, November 2026.
This study presents the first multi‐duration, sex‐stratified transcriptomic analysis of prolonged diapause in Colaphellus bowringi, revealing that extended dormancy is maintained by coordinated metabolic suppression and sustained activation of cytoprotective pathways (e.g., glutathione metabolism, autophagy).
Lili Huang, Yan Ni, Xin Ye, Xiaona Liu, Fangsen Xue, Haimin He   +5 more
wiley   +1 more source

Distribution and efficacy of ingested dsRNA targeting tissue-specific genes in the Argentine ant, Linepithema humile. [PDF]

PLoS One
Dittmann MA, Buczkowski G, Harpur BA.
europepmc   +1 more source

GmCRF1‐like2 Positively Regulates Resistance to Phytophthora sojae Through XTH‐Mediated Cell Wall Remodeling

Food and Energy Security, Volume 15, Issue 6, November/December 2026.
ABSTRACT Phytophthora root rot, caused by Phytophthora sojae, poses a significant threat to soybean (Glycine max) production worldwide. APETALA2/ethylene responsive factor (AP2/ERF) transcription factors play crucial roles in plant immune regulation, but the functions of subfamily cytokinin response factor (CRF) in soybean disease resistance remain ...
Wenjie Lin, Ziwu Xin, Jia Ma, Qiansheng Tian, Shunqi Ouyang, Saulo Fabricio da Silva Chaves, Jiangfang Guo, Wei Jiang, Chuanzhong Zhang   +8 more
wiley   +1 more source

4'-ThioRNA Substitution and Sense-Strand Segmentation for the Design of Functional Fully Modified siRNAs Targeting SARS-CoV-2. [PDF]

Chemistry
Nogi Y, Tsukimoto J, Saito-Tarashima N, Koma T, Nomaguchi M, Minakawa N.   +5 more
europepmc   +1 more source

Dichloroacetate Improves Animal Survival, Growth, Neuromuscular Activity, Mitochondrial Stress and Physiology, and Elevated Lactate in C. elegans pdha‐1 and dld‐1 RNAi Models of Pyruvate Dehydrogenase Complex Deficiency (PDCD)

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Pyruvate dehydrogenase complex (PDHc) deficiency (PDCD) is a primary mitochondrial disorder characterized by neurodevelopmental disability, altered intermediary metabolism, and early mortality. Dichloroacetate (DCA), a pyruvate analog, activates PDHc and remains under clinical investigation for treatment of PDCD.
Cristina Remes, Neal D. Mathew, Victoria Miranda, Suraiya Haroon, Tyler O'Hara, Vernon E. Anderson, Manuela Lavorato, Kelsey Keith, Rui Xiao, Eiko Nakamaru‐Ogiso, Marni J. Falk   +10 more
wiley   +1 more source

Foliar Application of dsRNA Suppresses Watermelon Bud Necrosis Virus Infection and Symptom Development in <i>Nicotiana benthamiana</i> and Cowpea Plants. [PDF]

Plants (Basel)
Gupta D, Gnanasekaran P, Singh OW, Manik S, Roy A, Mandal B.   +5 more
europepmc   +1 more source

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

RNAi-Mediated Knockdown of the Sodium Channel Auxiliary Subunit <i>TipE</i> Increases Pyrethroid-Associated Mortality and Reveals Metabolic Transcriptional Responses in <i>Megalurothrips usitatus</i>. [PDF]

Genes (Basel)
Wang L, Zhang S, Yuan L, Wu W, Wu H, Peng Z, Liang P, Zhang K, Wu S.   +8 more
europepmc   +1 more source

Insect immune systems: same same but different but still same. [PDF]

Front Immunol
Cardoso-Jaime V, Maya-Maldonado K, Powell S, Tikhe CV.   +3 more
europepmc   +1 more source