Results 11 to 20 of about 74,683 (214)
Application of RNA interference technology in pest control and its safety
浙江大学学报. 农业与生命科学版, 2022 RNA interference (RNAi) is a highly conserved gene-silencing phenomenon, induced by 20-30 nucleotide (nt) small molecules of non-coding RNA in vivo. Three non-coding RNAs, such as small interfering RNA (siRNA), microRNA (miRNA) and PIWI-interacting RNA ...
WANG Fang +7 more
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RNA Silencing in the Phytopathogenic Fungus Magnaporthe oryzae
Molecular Plant-Microbe Interactions, 2003 Systematic analysis of RNA silencing was carried out in the blast fungus Magnaporthe oryzae (formerly Magnaporthe grisea) using the enhanced green fluorescence protein (eGFP) gene as a model.
Naoki Kadotani +3 more
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Determination of the role of DDX3 a factor involved in mammalian RNAi pathway using an shRNA-expression library. [PDF]
PLoS ONE, 2013 RNA interference (RNAi) is an endogenous RNA-destruction phenomenon induced by certain double-stranded RNAs (dsRNAs). In RNAi, dsRNAs are processed into small interfering RNAs (siRNAs) which in turn trigger the cleavage of the target mRNA.
Vivi Kasim +3 more
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Molecular Therapy: Nucleic Acids, 2023 Small interfering RNA (siRNA) and short hairpin RNA (shRNA) are widely used as RNA interference (RNAi) reagents. Recently, truncated shRNAs that trigger RNAi in a Dicer-independent manner have been developed.
Atsushi Shibata +6 more
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Frontiers in Physiology, 2018 RNA interference (RNAi) is useful for controlling pests of agriculturally important crops. The soybean pod borer (SPB) is the most important soybean pest in Northeastern Asia.
Fanli Meng +8 more
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Viral Vectors Applied for RNAi-Based Antiviral Therapy
Viruses, 2020 RNA interference (RNAi) provides the means for alternative antiviral therapy. Delivery of RNAi in the form of short interfering RNA (siRNA), short hairpin RNA (shRNA) and micro-RNA (miRNA) have demonstrated efficacy in gene silencing for therapeutic ...
Kenneth Lundstrom
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The origin of RNA interference: Adaptive or neutral evolution?
PLoS Biology, 2022 The origin of RNA interference (RNAi) is usually explained by a defense-based hypothesis, in which RNAi evolved as a defense against transposable elements (TEs) and RNA viruses and was already present in the last eukaryotic common ancestor (LECA ...
Alessandro Torri +3 more
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Induction of Promoter DNA Methylation Upon High-Pressure Spraying of Double-Stranded RNA in Plants
Agronomy, 2021 Exogenous application of RNA molecules is a potent method to trigger RNA interference (RNAi) in plants in a transgene-free manner. So far, all exogenous RNAi (exo-RNAi) applications have aimed to trigger mRNA degradation of a given target.
Athanasios Dalakouras +1 more
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Are Viral Vectors Any Good for RNAi Antiviral Therapy?
Viruses, 2020 RNA interference (RNAi) represents a novel approach for alternative antiviral therapy. However, issues related to RNA delivery and stability have presented serious obstacles for obtaining good therapeutic efficacy.
Kenneth Lundstrom
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mSphere, 2017 Antiviral immunity in insects and plants is mediated by the RNA interference (RNAi) pathway in which viral long double-stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer enzymes.
Susan Schuster +4 more
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