Results 91 to 100 of about 389,403 (285)

Trends and frontiers of RNA methylation in cancer over the past 10 years: a bibliometric and visual analysis

Frontiers in Genetics
PurposeTo highlight the trends and frontiers of RNA methylation in cancer over the past 10 years.MethodsResearch publications on RNA methylation in cancer were retrieved from the Web of Science Core Collection database.
Bo-Na Liu, Xiao-Li Gao, Ying Piao
doaj   +1 more source

Topological Characterization of Human and Mouse m5C Epitranscriptome Revealed by Bisulfite Sequencing

International Journal of Genomics, 2018
Background. Compared with the well-studied 5-methylcytosine (m5C) in DNA, the role and topology of epitranscriptome m5C remain insufficiently characterized. Results.
Zhen Wei, Subbarayalu Panneerdoss, Santosh Timilsina, Jingting Zhu, Tabrez A. Mohammad, Zhi-Liang Lu, João Pedro de Magalhães, Yidong Chen, Rong Rong, Yufei Huang, Manjeet K. Rao, Jia Meng   +11 more
doaj   +1 more source

N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance [PDF]

, 2020
Noa Liberman, Zach Klapholz O’Brown, Andrew Earl, Konstantinos Boulias, Maxim V. Gerashchenko, Simon Yuan Wang, Colette Fritsche, Paul-Enguerrand Fady, Anna Dong, Vadim N. Gladyshev, Eric Lieberman Greer   +10 more
openalex   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Exaggerated CpH methylation in the autism-affected brain. [PDF]

, 2017
BackgroundThe etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the development of autism, we explored the ...
Arking, Dan E, Ellis, Shannon E, Gupta, Simone, Moes, Anna, West, Andrew B   +4 more
core   +1 more source

Malignant Evaluation and Clinical Prognostic Values of m6A RNA Methylation Regulators in Glioblastoma

Frontiers in Oncology, 2020
N6-methyladenosine (m6A) RNA methylation, the most common form of mRNA modification and regulated by the m6A RNA methylation regulators (“writers,” “erasers,” and “readers”), has been reported to be associated with the progression of the malignant tumor.
Jianyang Du, Jianyang Du, Kuiyuan Hou, Kuiyuan Hou, Shan Mi, Shan Mi, Hang Ji, Hang Ji, Shuai Ma, Shuai Ma, Yixu Ba, Yixu Ba, Shaoshan Hu, Rui Xie, Lei Chen, Lei Chen   +15 more
doaj   +1 more source

2'-O-ribose methylation of transfer RNA promotes recovery from oxidative stress in Saccharomyces cerevisiae [PDF]

, 2020
Lauren Endres, Rebecca E. Rose, Francis Doyle, T. Rähn, Bethany Lee, Jessica Seaman, William D. McIntyre, Daniele Fabris   +7 more
openalex   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma [PDF]

, 2010
Background The Sonic hedgehog (Shh) signaling pathway is critical for cell growth and differentiation. Impairment of this pathway can result in both birth defects and cancer.
Afzal, Mohammad, Castresana, Javier S, Eberhart, Charles G., Fan, Xing, Rey, Juan A, Shahi, Mehdi H, Sinha, Subrata   +6 more
core   +5 more sources

Statistical modeling of single-cell epitranscriptomics enabled trajectory and regulatory inference of RNA methylation

Cell Genomics
Summary: As a fundamental mechanism for gene expression regulation, post-transcriptional RNA methylation plays versatile roles in various biological processes and disease mechanisms.
Haozhe Wang, Yue Wang, Jingxian Zhou, Bowen Song, Gang Tu, Anh Nguyen, Jionglong Su, Frans Coenen, Zhi Wei, Daniel J. Rigden, Jia Meng   +10 more
doaj   +1 more source