Results 41 to 50 of about 323,185 (236)

Gene Expression Profile and Prognostic Value of m6A RNA Methylation Regulators in Hepatocellular Carcinoma

open access: yesJournal of Hepatocellular Carcinoma, 2021
Xian Chang,1,* Yang-Fan Lv,2,* Jing He,3,* Ya Cao,2 Chang-Qing Li,1 Qiao-Nan Guo2 1Department of Orthopedics, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing, 400037, People’s Republic of China; 2Department ...
Chang X   +5 more
doaj  

PROBer Provides a General Toolkit for Analyzing Sequencing-Based Toeprinting Assays [PDF]

open access: yes, 2017
A number of sequencing-based transcriptase drop-off assays have recently been developed to probe post-transcriptional dynamics of RNA-protein interaction, RNA structure, and RNA modification.
Aviran, Sharon   +3 more
core   +2 more sources

Chemical Modifications of Ribosomal RNA

open access: yes, 2022
AbstractCellular RNAs in all three kingdoms of life are modified with diverse chemical modifications. These chemical modifications expand the topological repertoire of RNAs, and fine-tune their functions. Ribosomal RNA in yeast contains more than 100 chemically modified residues in the functionally crucial and evolutionary conserved regions.
Sunny, Sharma, Karl-Dieter, Entian
openaire   +2 more sources

Crosstalk Between Four Types of RNA Modification Writers Characterizes the Tumor Immune Microenvironment Infiltration Patterns in Skin Cutaneous Melanoma

open access: yesFrontiers in Cell and Developmental Biology, 2022
The “writers” of four types of adenosine (A)-related RNA modifications (N6-methyladenosine, N1-methyladenosine, alternative polyadenylation, as well as A-to-inosine RNA editing) are closely related to the tumorigenesis and progression of many cancer ...
Shichao Zhang   +7 more
doaj   +1 more source

RAM function is dependent on Kapβ2-mediated nuclear entry [PDF]

open access: yes, 2014
Eukaryotic gene expression is dependent on the modification of the first transcribed nucleotide of pre-mRNA by the addition of the 7-methylguanosine cap.
Aregger   +24 more
core   +4 more sources

Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication

open access: yesmBio, 2021
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an ongoing global public crisis. Although viral RNA modification has been reported based on the transcriptome architecture, the types and ...
Xueyan Zhang   +9 more
doaj   +1 more source

Analysis of eight types of RNA modification regulators and their correlation with the prognosis in hepatocellular carcinoma

open access: yesFrontiers in Genetics, 2023
RNA modification plays important role in the occurrence and development of hepatocellular carcinoma. The best characterized RNA modification is m6A, while other kinds of RNA modifications have not been fully investigated in hepatocellular carcinoma (HCC).
Wan Qin, Chen Jin, Jun Zou
doaj   +1 more source

Regulatory role and mechanism of m6A RNA modification in human metabolic diseases

open access: yesMolecular Therapy: Oncolytics, 2021
Metabolic diseases caused by disorders in amino acids, glucose, lipid metabolism, and other metabolic risk factors show high incidences in young people, and current treatments are ineffective.
Yuliang Zhang   +8 more
doaj   +1 more source

The Role of m6A Ribonucleic Acid Modification in the Occurrence of Atherosclerosis

open access: yesFrontiers in Genetics, 2021
The N6-methyladenosine (m6A) modification is the most abundant epitranscriptomic modification in eukaryotic messenger RNA (mRNA). The m6A modification process is jointly regulated by various enzymes and proteins, such as methyltransferases, demethylases ...
Jie Fu   +8 more
doaj   +1 more source

Bionanomaterials from plant viruses [PDF]

open access: yes, 2015
Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
core   +2 more sources

Home - About - Disclaimer - Privacy