Results 1 to 10 of about 318,395 (185)
The origin of RNA precursors on exoplanets [PDF]
Science Advances, 2018 Researchers identify an “abiogenesis zone,” outside of which the building blocks of life cannot form photochemically.
Rimmer, Paul B +5 more
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RNA-binding protein immunoprecipitation as a tool to investigate plant miRNA processing interference by regulatory proteins of diverse origin [PDF]
Plant Methods, 2018 Background Due to the nature of viral RNA genomes, RNA viruses depend on many RNA-binding proteins (RBP) of viral and host origin for replication, dissemination and evasion of host RNA degradation pathways. Some viruses interfere with the microRNA (miRNA)
F. E. Marmisolle +2 more
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A continuous reaction network that produces RNA precursors [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance RNA may have been the original polymer to arise spontaneously on the early Earth through natural geochemistry. Although direct physical evidence regarding early Earth’s geochemistry is extremely limited, complex chemical reaction networks are thought to have played an important role in chemical evolution.
Ruiqin Yi +6 more
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Contribution of Small RNA Pathway to Interactions of Rice with Pathogens and Insect Pests
Rice, 2021 Small RNAs (sRNAs) are mainly classified into microRNAs (miRNAs) and small interfering RNAs (siRNAs) according to their origin. miRNAs originate from single-stranded RNA precursors, whereas siRNAs originate from double-stranded RNA precursors that are ...
Qin Feng +3 more
doaj +1 more source
The role of human Dicer-dsRBD in processing small regulatory RNAs. [PDF]
PLoS ONE, 2012 One of the most exciting recent developments in RNA biology has been the discovery of small non-coding RNAs that affect gene expression through the RNA interference (RNAi) mechanism.
Christopher Wostenberg +6 more
doaj +1 more source
Inflammation and Regeneration, 2023 Background Rheumatoid arthritis (RA) is characterized by chronic inflammation and resultant cartilage/bone destruction because of aberrantly activated osteoclasts.
Shinya Yari +8 more
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ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. [PDF]
PLoS ONE, 2013 A growing list of microRNAs (miRNAs) show aberrant expression patterns in hepatocellular carcinoma (HCC), but the regulatory mechanisms largely remain unclear.
Wan-Hsin Liu +7 more
doaj +1 more source
The Role of Adipocyte Precursors in Development and Obesity
Frontiers in Endocrinology, 2021 Maintenance of adipocyte precursors is critical for regulating metabolism and preventing obesity related disease. These precursors have been immortalized and studied in cellular models as well as—more recently—in animal models.
Tammy Ying +3 more
doaj +1 more source
Splicing of Messenger RNA Precursors
Science, 1987 A general mechanism for the splicing of nuclear messenger RNA precursors in eukaryotic cells has been widely accepted. This mechanism, which generates lariat RNAs possessing a branch site, seems related to the RNA-catalyzed reactions of self-splicing introns.
Sharp, P. A. +5 more
openaire +6 more sources
Non-Coding RNA Analyses of Seasonal Cambium Activity in Populus tomentosa
Cells, 2022 Non-coding RNA, known as long non-coding RNA (lncRNA), circular RNA (circRNA) and microRNA (miRNA), are taking part in the multiple developmental processes in plants.
Huimin Xu +10 more
doaj +1 more source