Results 241 to 250 of about 323,305 (331)

Skin-derived myeloid precursors and joint-resident fibroblasts spread psoriatic disease from skin to joints. [PDF]

Nat Immunol
Raimondo MG, Mohammadian H, Angeli MR, Alivernini S, Fedorchenko V, Huang K, Demmler R, Rhein P, Xu C, Li YN, Micheroli R, Winter Z, Rigau AR, Anchang CG, Soare A, Luber M, Labinsky H, Chang J, Günther C, Fearon U, Veale DJ, Ciccia F, Rech J, Sticherling M, Bäuerle T, Distler JHW, Kurowska-Stolarska MS, Mack M, Ekici AB, Croft AP, Distler O, Maric HM, Ospelt C, Cañete JD, D'Agostino MA, Schett G, Rauber S, Ramming A.   +37 more
europepmc   +1 more source

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang, Yunyi Zhang, Xiangyu Meng, Jianli Zhao, Yue Xing, Qian Ouyang, Ning Zhang, Huiping Chen, Nanyan Miao, Erwei Song, Di Huang   +10 more
wiley   +1 more source

Organoid-derived photoreceptor precursors enriched by CD9⁻CD81^mid sorting restore visual function in RCS rats. [PDF]

Stem Cell Res Ther
Wang C, Chen M, Fang Y, Fu Y, Lv Y, Zhang X, Li B, Bai Y, Li Q, Zeng Y, He XY, Liu H, Liu Y.   +12 more
europepmc   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

High molecular weight virion-associated RNA of vaccinia. A possible precursor to 8 to 12 S mRNA.

, 1977
Enzo Paoletti
openalex   +1 more source

Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity. [PDF]

NPJ Microgravity
Jones-Isaac K, Yeung CK, Bain J, Lidberg K, Yang J, Wang L, MacDonald J, Bammler T, Thummel KE, Corn M, Ruiz MV, Countryman S, Koenig P, Mann HH, Himmelfarb J, Kelly EJ.   +15 more
europepmc   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

RNA Editing Is Required for Efficient Excision of tRNAPhe from Precursors in Plant Mitochondria

, 1996
Anita Marchfelder, Axel Brennicke, Stefan Binder   +2 more
openalex   +1 more source

Gene regulatory mechanisms guiding bifurcation of inhibitory and excitatory neuron lineages in the mouse anterior brainstem. [PDF]

Elife
Kilpinen S, Virtanen L, Bodington Celma S, Bonsdorff A, Heliölä H, Achim K, Partanen J.   +6 more
europepmc   +1 more source