The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 angstrom resolution [PDF]
, 2008 Maturation of tRNA precursors into functional tRNA molecules requires trimming of the primary transcript at both the 5' and 3' ends. Cleavage of nucleotides from the 3' stem of tRNA precursors, releasing nucleotide diphosphates, is accomplished in ...
Blagova, Elena V. +5 more
core +2 more sources
A database of microRNA expression patterns in Xenopus laevis [PDF]
, 2015 MicroRNAs (miRNAs) are short, non-coding RNAs around 22 nucleotides long. They inhibit gene expression either by translational repression or by causing the degradation of the mRNAs they bind to.
A Hemmati-Brivanlou +46 more
core +8 more sources
MicroRNA-like RNAs from the same miRNA precursors play a role in cassava chilling responses [PDF]
, 2017 MicroRNAs (miRNAs) are known to play important roles in various cellular processes and stress responses. MiRNAs can be identified by analyzing reads from high-throughput deep sequencing.
Chen, Xin +5 more
core +3 more sources
Diversity of Endonuclease V: From DNA Repair to RNA Editing
Biomolecules, 2015 Deamination of adenine occurs in DNA, RNA, and their precursors via a hydrolytic reaction and a nitrosative reaction. The generated deaminated products are potentially mutagenic because of their structural similarity to natural bases, which in turn leads
Isao Kuraoka
doaj +1 more source
Helical defects in microRNA influence protein binding by TAR RNA binding protein. [PDF]
PLoS ONE, 2015 MicroRNAs (miRNAs) are critical post-transcriptional regulators of gene expression. Their precursors have a globally A-form helical geometry, which prevents most proteins from identifying their nucleotide sequence. This suggests the hypothesis that local
Roderico Acevedo +3 more
doaj +1 more source
The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. [PDF]
, 2017 Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation ...
Honda, Shozo +5 more
core +2 more sources
Precursors to small molecular weight RNA components [PDF]
FEBS Letters, 1975 Metabolically long-lived RNA components such as tRNA and rRNA are formed from unstable larger precursors [ 1,2] . Baby Hamster Kidney cells (BHK-2 1 cells) contain four small mol. wt RNA components (sm RNA) with a metabolic half-life of 5-7 days [3] . The size of these components (D, C, A, and L) was determined to be from 145 to 235 nucleotides based ...
Frederiksen, Sune, Hellung-Larsen, Per
openaire +2 more sources
Argonaute-dependent small RNAs derived from single-stranded non-structured precursors
Frontiers in Genetics, 2014 A general feature of Argonaute-dependent small RNAs is their base-paired precursor structures, and precursor duplex structures are often required for confident annotation of miRNA genes.
Li-Ling eChak +2 more
doaj +1 more source
The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana. [PDF]
PLoS Genetics, 2014 The RNA exosome is the major 3'-5' RNA degradation machine of eukaryotic cells and participates in processing, surveillance and turnover of both nuclear and cytoplasmic RNA.
Heike Lange +13 more
doaj +1 more source
Detection and Phylogenetic Analysis of Group 1 Coronaviruses in South American Bats
Emerging Infectious Diseases, 2008 Bat coronaviruses (Bt-CoVs) are thought to be the precursors of severe acute respiratory syndrome coronavirus. We detected Bt-CoVs in 2 bat species from Trinidad.
Christine V.F. Carrington +9 more
doaj +1 more source