When did Life Likely Emerge on Earth in an RNA-First Process? [PDF]
19. Benner, S.A., Bell, E.A., Biondi, E., Brasser, R., Carell, T.,
Kim, H-J., Mojzsis, S.J., Omran, A., Pasek, M.A., and Trail, D. (2020) When
did Life Likely Emerge on Earth in an RNA-First Process? ChemSystemsChem 2,
e1900035, 2019 The widespread presence of ribonucleic acid (RNA) catalysts and cofactors in Earth's biosphere today suggests that RNA was the first biopolymer to support Darwinian evolution. However, most "path-hypotheses" to generate building blocks for RNA require reduced nitrogen-containing compounds not made in useful amounts in the CO2-N2-H2O atmospheres of the ...
arxiv +1 more source
Characterization of the Small RNA Transcriptome of the Marine Coccolithophorid, Emiliania huxleyi [PDF]
, 2016 Small RNAs (smRNAs) control a variety of cellular processes by silencing target genes at the transcriptional or post-transcription level. While extensively studied in plants, relatively little is known about smRNAs and their targets in marine ...
Carrasco, Estela +7 more
core +3 more sources
Diversity of Endonuclease V: From DNA Repair to RNA Editing
Biomolecules, 2015 Deamination of adenine occurs in DNA, RNA, and their precursors via a hydrolytic reaction and a nitrosative reaction. The generated deaminated products are potentially mutagenic because of their structural similarity to natural bases, which in turn leads
Isao Kuraoka
doaj +1 more source
Emergence of information transmission in a prebiotic RNA reactor [PDF]
Phys. Rev. Lett. 107, 018101 (2011), 2011 A poorly understood step in the transition from a chemical to a biological world is the emergence of self-replicating molecular systems. We study how a precursor for such a replicator might arise in a hydrothermal RNA reactor, which accumulates longer sequences from unbiased monomer influx and random ligation. In the reactor, intra- and inter-molecular
arxiv +1 more source
Argonaute-dependent small RNAs derived from single-stranded non-structured precursors
Frontiers in Genetics, 2014 A general feature of Argonaute-dependent small RNAs is their base-paired precursor structures, and precursor duplex structures are often required for confident annotation of miRNA genes.
Li-Ling eChak +2 more
doaj +1 more source
Identification of precursor transcripts for 6 novel miRNAs expands the diversity on the genomic organisation and expression of miRNA genes in rice [PDF]
, 2008 The plant miRNAs represent an important class of endogenous small RNAs that guide cleavage of an mRNA target or repress its translation to control development and adaptation to stresses.
Bangratz, Martine +15 more
core +1 more source
The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana. [PDF]
PLoS Genetics, 2014 The RNA exosome is the major 3'-5' RNA degradation machine of eukaryotic cells and participates in processing, surveillance and turnover of both nuclear and cytoplasmic RNA.
Heike Lange +13 more
doaj +1 more source
Precursors of U4 small nuclear RNA. [PDF]
The Journal of cell biology, 1984 The processing and ribonucleoprotein assembly of U4 small nuclear RNA has been investigated in HeLa cells. After a 45-min pulse label with [3H]uridine, a set of apparently cytoplasmic RNAs was observed migrating just behind the gel electrophoretic position of mature U4 RNA.
Thoru Pederson +3 more
openaire +2 more sources
Detection and Phylogenetic Analysis of Group 1 Coronaviruses in South American Bats
Emerging Infectious Diseases, 2008 Bat coronaviruses (Bt-CoVs) are thought to be the precursors of severe acute respiratory syndrome coronavirus. We detected Bt-CoVs in 2 bat species from Trinidad.
Christine V.F. Carrington +9 more
doaj +1 more source
Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]
, 2013 RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif +2 more
core +3 more sources