Results 241 to 250 of about 442,476 (336)

Stress granules at the crossroads of retroviral replication and antiviral immunity: mechanisms and therapeutic opportunities. [PDF]

Mol Biol Rep
Akbarin MM, Farjami Z, Álvarez HR.
europepmc   +1 more source

Self-inactivating retroviral vectors with improved RNA processing

Gene Therapy, 2004
J. Kraunus, J. Kraunus, D. Schaumann, J. Meyer, U. Modlich, B. Fehse, G. Brandenburg, D. Laer, H. Klump, A. Schambach, J. Bohne, C. Baum, C. Baum   +12 more
semanticscholar   +1 more source

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

Advanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng, Isaak Decoene, Hanna Svitina, Ioannis Papantoniou   +3 more
wiley   +1 more source

Transcriptional signatures of rapid protection from Sudan virus infection by a single dose of a vesicular stomatitis virus-based vaccine. [PDF]

PLoS Pathog
Doratt BM, Wagner SB, Malherbe DC, Smith G, Marzi A, Messaoudi I.   +5 more
europepmc   +1 more source

SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease.

Seminars in Cell and Developmental Biology, 2014
Darrick K. Li, S. Tisdale, F. Lotti, L. Pellizzoni   +3 more
semanticscholar   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

Molecular and Functional Platelet Abnormalities in Myeloproliferative Neoplasms. [PDF]

Cells
Wang AX, Guo BB, Linden MD.
europepmc   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

Structural insights into disease-associated mutations in the microRNA processing machinery. [PDF]

Exp Mol Med
Lee H, Lee J, Roh SH.
europepmc   +1 more source