Results 1 to 10 of about 778,047 (203)
RNA World with Inhibitors [PDF]
EntropyDuring the evolution of the RNA World, compartments, which were fragments of space surrounded by a primitive lipid membrane, had to have emerged. These led eventually to the formation of modern cellular membranes.
Jaroslaw Synak +3 more
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Order and Complexity in the RNA World [PDF]
Life, 2023 The basic idea of the RNA world as an early step towards life relies on a molecular evolution process based on self-replicating RNA strands. It is probably the oldest and most convincing model for efficient prebiotic evolution.
Christian Mayer
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The RNA world of fungal pathogens. [PDF]
PLoS Pathogens, 2023 Jürgen Manchot Stiftung http://dx.doi.org/10.13039 ...
Srimeenakshi Sankaranarayanan +3 more
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RNA World Modeling: A Comparison of Two Complementary Approaches [PDF]
Entropy, 2022 The origin of life remains one of the major scientific questions in modern biology. Among many hypotheses aiming to explain how life on Earth started, RNA world is probably the most extensively studied.
Jaroslaw Synak +2 more
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Kin Selection in the RNA World [PDF]
Life, 2017 Various steps in the RNA world required cooperation. Why did life’s first inhabitants, from polymerases to synthetases, cooperate? We develop kin selection models of the RNA world to answer these questions.
Samuel R. Levin, Stuart A. West
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Revisiting the Extinction of the RNA World. [PDF]
Biochemistry, 2022 The ribozyme world is thought to have evolved the burdensome complexity of peptide and protein synthesis because the 20 amino acid side chains are catalytically superior. Instead, I propose that the Achilles heel of the RNA world that led to the extinction of riboorganisms was RNA's polyanionic charges that could not be covalently neutralized stably by
Forster AC.
europepmc +5 more sources
Rethinking the tools of the RNA world [PDF]
eLife, 2018 An artificially evolved ribozyme can catalyse the synthesis of RNA by using trinucleotide triphosphates as building blocks.
Antony Crisp, Thomas Carell
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From RNA World to SARS-CoV-2: The Edited Story of RNA Viral Evolution [PDF]
Cells, 2021 The current SARS-CoV-2 pandemic underscores the importance of understanding the evolution of RNA genomes. While RNA is subject to the formation of similar lesions as DNA, the evolutionary and physiological impacts RNA lesions have on viral genomes are ...
Zachary W. Kockler, Dmitry A. Gordenin
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Uni-directional polymerization leading to homochirality in the RNA world [PDF]
, 2005 The differences between uni-directional and bi-directional polymerization are considered. The uni-directional case is discussed in the framework of the RNA world. Similar to earlier models of this type, where polymerization was assumed to proceed in a bi-
Andersen, A. C. +3 more
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Key steps from the “RNA World” to the “DNA World” [PDF]
BIO Web of Conferences, 2014 In the « RNA World » hypothesis of the origin of life, RNAs are assumed to be the central macromolecules able to self-replicate, conserve information and catalyze the reactions necessary for a primitive metabolism and many enzymatic cofactors may be ...
Renard B.-L. +3 more
doaj +2 more sources