Results 31 to 40 of about 778,146 (302)
A Polyaddition Model for the Prebiotic Polymerization of RNA and RNA-Like Polymers
Life, 2020 Implicit in the RNA world hypothesis is that prebiotic RNA synthesis, despite occurring in an environment without biochemical catalysts, produced the long RNA polymers which are essential to the formation of life.
Alex Spaeth, Mason Hargrave
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Genetics and Molecular Biology, 2014 One of the major developments that resulted from the human genome sequencing projects was a better understanding of the role of non-coding RNAs (ncRNAs). NcRNAs are divided into several different categories according to size and function; however, one shared feature is that they are not translated into proteins. In this review, we will discuss relevant
Dogini, Danyella Barbosa +5 more
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What Does "the RNA World" Mean to "the Origin of Life"? [PDF]
Life (Basel), 2017 Ma W.
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Life, 2023 How functional peptides may have arisen is a significant problem for the scenario of the RNA world. An attractive idea, the direct RNA template (DRT) hypothesis, proposes that RNA molecules can bind amino acids specifically and promote the synthesis of ...
Yu Shi, Chunwu Yu, Wentao Ma
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Annual Review of Plant Biology, 2023 My research career started with an ambition to work out how genes are regulated in plants. I tried out various experimental systems—artichoke tissue culture in Edinburgh; soybean root nodules in Montreal; soybean hypocotyls in Athens, Georgia; and cereal aleurones in Cambridge—but eventually I discovered plant viruses.
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Journal of Cell Science, 2003 Small RNAs have burst on the scene as ubiquitous, versatile repressors of gene expression in plants, animals and many fungi. These tiny RNAs (∼21-26 nt), which induce silencing through homologous sequence interactions, come in many guises: short interfering (si) RNAs ([Elbashir et al., 2001][1]),
Marjori Matzke, E. Jean Finnegan
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Lipid-Assisted Polymerization of Nucleotides
Life, 2019 In addition to being one of the proponents of the “Lipid World hypothesis”, David Deamer, together with other colleagues, pioneered studies involving formation of RNA-like oligomers from their ‘non-activated’, prebiotically ...
Felix Olasagasti, Sudha Rajamani
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The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA. [PDF]
, 2011 In the early 'RNA world' stage of life, RNA stored genetic information and catalyzed chemical reactions. However, the RNA world eventually gave rise to the DNA-RNA-protein world, and this transition included the 'genetic takeover' of information storage ...
Chen, Irene A +4 more
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Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]
, 2014 Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
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Methanol in the RNA world: An astrochemical perspective
Frontiers in Astronomy and Space Sciences, 2022 The role and relevance of methanol in the origin and structure of the RNA world is discussed. Methanol is a pivotal, renewable, and regenerable source from which almost all chemical materials, simple or complex, can be accessed.
Thomas Mathew +2 more
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