Results 21 to 30 of about 291,851 (290)

Trinity of G-tetrads and origin of translation

open access: yesBiology Direct, 2022
Background The RNA world hypothesis cannot address most of the questions of the origin of life without violating the continuity principle (small Darwinian steps without foresight and miracles).
Besik Kankia
doaj   +1 more source

Towards an RNA/Peptides World by the Direct RNA Template Mechanism: The Emergence of Membrane-Stabilizing Peptides in RNA-Based Protocells

open access: yesLife, 2023
How functional peptides may have arisen is a significant problem for the scenario of the RNA world. An attractive idea, the direct RNA template (DRT) hypothesis, proposes that RNA molecules can bind amino acids specifically and promote the synthesis of ...
Yu Shi, Chunwu Yu, Wentao Ma
doaj   +1 more source

The Way forward for the Origin of Life: Prions and Prion-Like Molecules First Hypothesis

open access: yesLife, 2021
In this paper the hypothesis that prions and prion-like molecules could have initiated the chemical evolutionary process which led to the eventual emergence of life is reappraised.
Sohan Jheeta   +3 more
doaj   +1 more source

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]

open access: yes, 2020
Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu   +2 more
core   +2 more sources

An Aminoisoxazole‐Based Proto‐RNA

open access: yesChemistryEurope, 2023
The RNA world hypothesis predicts that life started with the development of replicating and catalytically active RNA, which evolved in a process of molecular evolution to increasingly complex chemical structures.
Felix Xu   +4 more
doaj   +1 more source

Arginine cofactors on the polymerase ribozyme. [PDF]

open access: yesPLoS ONE, 2011
The RNA world hypothesis states that the early evolution of life went through a stage in which RNA served both as genome and as catalyst. The central catalyst in an RNA world organism would have been a ribozyme that catalyzed RNA polymerization to ...
Chengguo Yao   +4 more
doaj   +1 more source

Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]

open access: yes, 2014
Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core   +1 more source

Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization

open access: yesNature Communications, 2021
Prebiotic compartmentalization could prove essential for the evolution of life. Guo et al. show that liquid-liquid separation in an aqueous two-phase system driven by evaporation may already suffice to facilitate chemical processes required for the RNA ...
Wei Guo   +6 more
doaj   +1 more source

The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity

open access: yesLife, 2022
The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
doaj   +1 more source

The Old and New RNA World

open access: yesActa Societatis Botanicorum Poloniae, 2014
Among the numerous hypotheses offering a scenario for the origin of life on Earth, the one called “The RNA World” has gained the most attention. According to this hypothesis RNA acted as a genetic information storage material, as a catalyst of all ...
Zofia Szweykowska-Kulińska
doaj   +1 more source

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