Results 31 to 40 of about 291,851 (290)

The Origin of Life: Models and Data. [PDF]

open access: yes, 2017
A general framework for conventional models of the origin of life (OOL) is the specification of a 'privileged function.' A privileged function is an extant biological function that is excised from its biological context, elevated in importance over other
Lanier, Kathryn A, Williams, Loren Dean
core   +1 more source

Applications of phage-derived RNA-based technologies in synthetic biology

open access: yesSynthetic and Systems Biotechnology, 2020
As the most abundant biological entities with incredible diversity, bacteriophages (also known as phages) have been recognized as an important source of molecular machines for the development of genetic-engineering tools.
Wenhui Zhang, Qiong Wu
doaj   +1 more source

Primordial soup or vinaigrette: did the RNA world evolve at acidic pH?

open access: yesBiology Direct, 2012
Background The RNA world concept has wide, though certainly not unanimous, support within the origin-of-life scientific community. One view is that life may have emerged as early as the Hadean Eon 4.3-3.8 billion years ago with an atmosphere of high CO2 ...
Bernhardt Harold S, Tate Warren P
doaj   +1 more source

The RNA World: 4,000,000,050 years old

open access: yesLife, 2015
The RNA World is now some four billion years behind us, but only recently turned 50 as a human hypothesis. [...]
Niles Lehman
doaj   +1 more source

A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]

open access: yes, 2013
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith   +6 more
core   +2 more sources

Meta-analysis of honey bee neurogenomic response links deformed wing virus type A to precocious behavioral maturation [PDF]

open access: yes, 2020
Crop pollination by the western honey bee Apis mellifera is vital to agriculture but threatened by alarmingly high levels of colony mortality, especially in Europe and North America.
Ahmed, Amy Cash   +7 more
core   +1 more source

Competing Endogenous RNA Regulations in Neurodegenerative Disorders: Current Challenges and Emerging Insights

open access: yesFrontiers in Molecular Neuroscience, 2018
The past decade has witnessed exciting breakthroughs that have contributed to the richness and complexity of a burgeoning modern RNA world, and one particular breakthrough—the competing endogenous RNA (ceRNA) hypothesis—has been described as the “Rosetta
Yifei Cai, Jun Wan, Jun Wan
doaj   +1 more source

Comparative analysis of RNA families reveals distinct repertoires for each domain of life.

open access: yesPLoS Computational Biology, 2012
The RNA world hypothesis, that RNA genomes and catalysts preceded DNA genomes and genetically-encoded protein catalysts, has been central to models for the early evolution of life on Earth.
Marc P Hoeppner   +2 more
doaj   +1 more source

Twenty years of "Lipid World": a fertile partnership with David Deamer [PDF]

open access: yes, 2019
"The Lipid World" was published in 2001, stemming from a highly effective collaboration with David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in Israel.
Kahana, Amit   +2 more
core   +1 more source

Nonenzymatic RNA-templated Synthesis of N3′→P5′ Phosphoramidate DNA

open access: yesBio-Protocol, 2020
The RNA world hypothesis describes a scenario where early life forms relied on RNA to govern both inheritance and catalyze useful chemical reactions.
Derek O'Flaherty   +2 more
doaj   +1 more source

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