Results 1 to 10 of about 330,568 (380)

RNAi [PDF]

Cell, 2000
Zamore, Phillip D, Tuschl, Thomas, Sharp, Phillip A, Bartel, David P   +3 more
openaire   +2 more sources

Genetic Variability and Resistance to Orobanche in Oriental Nicotiana tabacum L. [PDF]

Agrotechniques in Industrial Crops, 2023
Broomrape as an obligate parasite that threatens tobacco production (Nicotiana tabacum L.), has destructive effects on its characteristics. The reduction in yield caused by this parasite is so great that sometimes farmers are forced to leave their fields
Reza Darvishzadeh, Sanaz Khalifani
doaj   +1 more source

Individual and Interactive Effects of Nitrogen and Phosphorus on Drought Stress Response and Recovery in Maize Seedlings

Agriculture, 2023
Plants have an inherent mechanism for perceiving drought stress and respond through a series of physiological, cellular and molecular changes for maintaining physiological water balance.
Temesgen Assefa Gelaw, Kavita Goswami, Neeti Sanan-Mishra   +2 more
doaj   +1 more source

Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1.

New England Journal of Medicine, 2021
BACKGROUND Primary hyperoxaluria type 1 (PH1) is a rare genetic disease caused by hepatic overproduction of oxalate that leads to kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis. Lumasiran, an investigational RNA interference (RNAi)
Sander F. Garrelfs, Y. Frishberg, S. Hulton, M. Koren, W. O'Riordan, P. Cochat, G. Deschênes, H. Shasha-Lavsky, J. Saland, W. V. van’t Hoff, D. Fuster, D. Magen, S. Moochhala, Gesa Schalk, E. Simkova, J. Groothoff, David J. Sas, K. Meliambro, Jiandong Lu, M. Sweetser, P. Garg, A. Vaishnaw, J. Gansner, T. McGregor, J. Lieske   +24 more
semanticscholar   +1 more source

Coordinated Action of RTBV and RTSV Proteins Suppress Host RNA Silencing Machinery

Microorganisms, 2022
RNA silencing is as an adaptive immune response in plants that limits the accumulation or spread of invading viruses. Successful virus infection entails countering the RNA silencing machinery for efficient replication and systemic spread in the host. The
Abhishek Anand, Malathi Pinninti, Anita Tripathi, Satendra Kumar Mangrauthia, Neeti Sanan-Mishra   +4 more
doaj   +1 more source

Priming by High Temperature Stress Induces MicroRNA Regulated Heat Shock Modules Indicating Their Involvement in Thermopriming Response in Rice

Life, 2021
Rice plants often encounter high temperature stress, but the associated coping strategies are poorly understood. It is known that a prior shorter exposure to high temperature, called thermo-priming, generally results in better adaptation of the plants to
Akhilesh Kumar Kushawaha, Ambreen Khan, Sudhir Kumar Sopory, Neeti Sanan-Mishra   +3 more
doaj   +1 more source

piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair

Communications Biology, 2021
Mallick et al. investigate the role of the piRNA, piR-39980, and doxorubicin (DOX) resistance in fibrosarcoma, finding that piR-39980 is less expressed in DOX-resistant HT1080 fibrosarcoma cells.
Basudeb Das, Neha Jain, Bibekanand Mallick   +2 more
doaj   +1 more source

RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies

Journal of Pharmacology and Experimental Therapeutics, 2022
RNA interference (RNAi) provides researchers with a versatile means to modulate target gene expression. The major forms of RNAi molecules, genome-derived microRNAs (miRNAs) and exogenous small interfering RNAs (siRNAs), converge into RNA-induced ...
G. Traber, A. Yu
semanticscholar   +1 more source

Asian Citrus Psyllid RNAi Pathway – RNAi evidence [PDF]

Scientific Reports, 2016
AbstractDiaphorina citri, known as the Asian citrus psyllid, is an important pest of citrus because it transmits a phloem-limited bacteria strongly implicated in huanglongbing (citrus greening disease). Emerging biotechnologies, such as RNA interference, could provide a new sustainable and environmentally friendly strategy for the management of this ...
Taning, Nji Tizi Clauvis, Andrade, Eduardo C, Hunter, Wayne B, Christiaens, Olivier, Smagghe, Guy   +4 more
openaire   +3 more sources

Bacterial Delivery of RNAi Effectors: Transkingdom RNAi [PDF]

Journal of Visualized Experiments, 2010
RNA interference (RNAi) represents a high effective mechanism for specific inhibition of mRNA expression. Besides its potential as a powerful laboratory tool, the RNAi pathway appears to be promising for therapeutic utilization. For development of RNA interference (RNAi)-based therapies, delivery of RNAi-mediating agents to target cells is one of the ...
Lage, Hermann, Krühn, Andrea
openaire   +2 more sources