Results 191 to 200 of about 330,568 (380)

Reaping the rewards of RNAi [PDF]

, 2003
Jonathan B Weitzman
openalex   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

Pest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden, Gözde Güney, Michael Rostás, Stefan Scholten   +3 more
wiley   +1 more source

A genome-wide RNAi screen identifies determinants of human embryonic stem cells [PDF]

, 2012
Na Yu Chia
openalex   +1 more source

An RNA interference biopesticide reduces reproduction of the honey bee parasite Varroa destructor by down‐regulating embryo development pathways

Pest Management Science, EarlyView.
Varroa destructor mites exposed to dsRNA specific in sequence to a V. destructor calmodulin gene significantly effected gene expression of adult female mites sampled 5 days after entering a honey bee brood cell to reproduce. Significantly down‐regulated genes included Calmodulin and were associated with calcium ion binding and embryo developmental ...
Zoe E Smeele, Rose A McGruddy, James W Baty, Brian Manley, Kenneth Narva, Emma De Neef, Eric RL Gordon, Upendra K Devisetty, Katie Youngs, Antoine Felden, Philip J Lester   +10 more
wiley   +1 more source

Evaluating the potential of RNA interference for control of striped cucumber beetle, Acalymma vittatum (Fabricius) (Coleoptera: Chrysomelidae)

Pest Management Science, EarlyView.
SCB has a robust RNAi response to injected dsRNA, but oral RNAi is less efficient. Nucleases do not appear to be responsible for the discrepancy, suggesting other factors are involved. Abstract BACKGROUND The striped cucumber beetle (SCB) is a serious pest of cucurbit crops, causing damage both by feeding on plants and by vectoring plant diseases ...
Emine Kaplanoglu, Félix Longpré, Cam Donly   +2 more
wiley   +1 more source

Endocytosed dsRNAs induce lysosomal membrane permeabilization that allows cytosolic dsRNA translocation for Drosophila RNAi responses [PDF]

Tsubasa Tanaka, Tamaki Yano, Shingo Usuki, Y. H. Seo, Kento Mizuta, Maho Okaguchi, Maki Yamaguchi, Kazuko Hanyu‐Nakamura, Noriko Toyama‐Sorimachi, Katja Brückner, Akira Nakamura   +10 more
openalex   +1 more source

Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates [PDF]

, 2007
Dong Sung An, Robert E. Donahue, Masakazu Kamata, Betty Poon, Mark E. Metzger, Si‐Hua Mao, Aylin Bonifacino, Allen E. Krouse, Jean‐Luc Darlix, David Baltimore, F. Xiao‐Feng Qin, Irvin S. Y. Chen   +11 more
openalex   +1 more source

Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi

Science, 2002
Thomas A. Volpe, C. Kidner, Ira M. Hall, G. Teng, S. Grewal, R. Martienssen   +5 more
semanticscholar   +1 more source

Glucosinolate hydrolysis products suppress entomopathogenic nematodes in vitro but do not protect sequestering flea beetle larvae in vivo

Pest Management Science, EarlyView.
The flea beetle's glucosinolate‐based chemical defense fails to protect larvae from nematode infection. However, the defense inhibits the nematode's symbiotic bacteria, thereby potentially impairing nematode reproduction and biocontrol success. Abstract BACKGROUND The efficacy of entomopathogenic nematodes (EPNs) in the biological control of insect ...
Johannes Körnig, Vojtech Beneš, Christin Manthey, Michael Reichelt, Grit Kunert, Christian Paetz, Johanna Kutzschbach, Paula Lampe, Martin Kaltenpoth, Franziska Beran   +9 more
wiley   +1 more source

RNAi-based drug design: considerations and future directions

Nature reviews. Drug discovery
Qi Tang, Anastasia Khvorova
semanticscholar   +1 more source