Results 201 to 210 of about 195,676 (344)

Myosin 15 participates in assembly and remodeling of the presynapse. [PDF]

J Cell Biol
Petzoldt AG, Escher MJF, Turrel O, Gimber N, Schedina IM, Walter S, Götz TWB, Maglione M, Toppe D, Matkovic-Rachid T, Neumann A, Lützkendorf J, Schmoranzer J, Lehmann M, Großhans J, Sigrist SJ.   +15 more
europepmc   +1 more source

Short hairpin type of dsRNAs that are controlled by tRNAVal promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells [PDF]

, 2003
Hiroshi Kawasaki
openalex   +1 more source

Identifying potentially suitable and accessible refugia to mitigate impacts of an emerging disease on a rare tree

Conservation Biology, EarlyView.
Abstract Identifying refugia from emerging threats is vital to ensure the persistence of rare and threatened species, but modeling habitat distribution for these species is challenging and the role of people in refuge management is rarely considered. Myrtle rust is an emerging infectious disease that represents a grave threat to the rare wetland tree ...
Sarah M. Herbert, Stephanie A. Tomscha, Hao Ran Lai, Rubianca Benavidez, Colan G. Balkwill, Pearl R. Ruston, Bethanna Jackson, Julie R. Deslippe   +7 more
wiley   +1 more source

Targeting phospholipase PLAG-15 promotes healthy aging in <i>C. elegans</i> via lysosomal-related genes. [PDF]

iScience
van der Rijt S, Molenaars M, Kamble R, Li W, Schomakers BV, Dane AD, Denis SW, van Weeghel M, Vaz FM, Tammaro A, Janssens GE, Gao AW, Houtkooper RH.   +12 more
europepmc   +1 more source

RNAi: Mammalian oocytes do it without RNA-dependent RNA polymerase [PDF]

, 2003
Paula Stein, Petr Svoboda, Martin Anger, Richard M. Schultz   +3 more
openalex   +1 more source

Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids

Cell Research, 2019
Yan-Peng Xu, Y. Qiu, Boya Zhang, Guilai Chen, Qi Chen, Miao Wang, Fan Mo, Jiuyue Xu, Jin Wu, Rong-Rong Zhang, Mengli Cheng, N. Zhang, Bao Lyu, Wenliang Zhu, Menghua Wu, Qing Ye, Da Zhang, Jianghong Man, Xiao-Feng Li, Jie Cui, Zhiheng Xu, Baoyang Hu, Xi Zhou, C. Qin   +23 more
semanticscholar   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Mutant alleles of the Caenorhabditis elegans rde-1 gene identified through chemical mutagenesis of an snRNA misprocessing reporter. [PDF]

G3 (Bethesda)
Waddell BM, Wu CW.
europepmc   +1 more source

Similar behaviour of single-strand and double-strand siRNAs suggests they act through a common RNAi pathway [PDF]

, 2003
Torgeir Holen
openalex   +1 more source

Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development

The FEBS Journal, EarlyView.
Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran, Hannah R. Littel, Natalya M. Wells, Johnnie Turner, Gloriana Campos, Sree Venigalla, Elicia A. Estrella, Partha S. Ghosh, Audrey L. Daugherty, Seth A. Stafki, Louis M. Kunkel, A. Reghan Foley, Sandra Donkervoort, Carsten G. Bönnemann, Laura Toledo‐Bravo de Laguna, Andres Nascimento, Daniel Natera‐de Benito, Isabelle Draper, Christine C. Bruels, Christina A. Pacak, Peter B. Kang   +20 more
wiley   +1 more source