Results 211 to 220 of about 323,847 (388)
Exon-specific RNAi: A tool for dissecting the functional relevance of alternative splicing [PDF]
, 2002 Alicia M. Celotto, Brenton R. Graveley
openalex +1 more source
Vinpocetine Overcomes Paclitaxel Resistance in a Triple‐Negative Breast Cancer Cell Line
Cell Biology International, EarlyView.ABSTRACT Paclitaxel is a first‐line treatment for triple‐negative breast cancer (TNBC), but its efficacy is commonly limited by tumor‐cell resistance. Vinpocetine is a well‐tolerated dietary supplement with pleiotropic cellular effects, including potential anti‐tumor activity.
Hsiao‐Hui Kuo +3 more
wiley +1 more source
Gankyrin‐Protein Interactions in GI Cancers: A Novel Target of New Therapeutics
Chronic Diseases and Translational Medicine, EarlyView.ABSTRACT Gankyrin (PSMD10) is a 25 kDa oncogenic protein and regulatory subunit of the 26S proteasome, characterized by a sevenfold ankyrin repeat domain. Gankyrin is overexpressed in various malignancies, particularly gastrointestinal (GI) cancers. Gankyrin contributes to tumorigenesis by modulating key signaling pathways and engaging in oncogenic ...
Shuang Li +4 more
wiley +1 more source
Loss of the Putative RNA-Directed RNA Polymerase RRF-3 Makes C. elegans Hypersensitive to RNAi [PDF]
, 2002 Femke Simmer +7 more
openalex +1 more source
Making Two out of One: Kinesin Motors Driving Plant Cell Division
Cytoskeleton, EarlyView.ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley +1 more source
RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E [PDF]
, 2002 Jason R. Kennerdell +2 more
openalex +1 more source
Developmental Dynamics, EarlyView.Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu +4 more
wiley +1 more source
Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster
G3: Genes, Genomes, Genetics, 2020 Grace A. Parker +5 more
doaj +1 more source