AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration [PDF]
Michelle E. McClements +5 more
openalex +1 more source
Protanopia (red color-blindness) in medaka: a simple system for producing color-blind fish and testing their spectral sensitivity [PDF]
BACKGROUND: Color perception is important for fish to survive and reproduce in nature. Visual pigments in the retinal photoreceptor cells are responsible for receiving light stimuli, but the function of the pigments in vivo has not been directly ...
Noriko Homma +4 more
core +1 more source
Adaptive genomic evolution of opsins reveals that early mammals flourished in nocturnal environments
Background Based on evolutionary patterns of the vertebrate eye, Walls (1942) hypothesized that early placental mammals evolved primarily in nocturnal habitats. However, not only Eutheria, but all mammals show photic characteristics (i.e.
Rui Borges +5 more
doaj +1 more source
Functional characterization of the rod visual pigment of the echidna (Tachyglossus aculeatus), a basal mammal [PDF]
Monotremes are the most basal egg-laying mammals comprised of two extant genera, which are largely nocturnal. Visual pigments, the first step in the sensory transduction cascade in photoreceptors of the eye, have been examined in a variety of vertebrates,
BICKELMANN, CONSTANZE +3 more
core
Spatially differentiated expression of quadruplicated green-sensitive RH2 opsin genes in zebrafish is determined by proximal regulatory regions and gene order to the locus control region [PDF]
BACKGROUND: Fish are remarkably diverse in repertoires of visual opsins by gene duplications. Differentiation of their spatiotemporal expression patterns and absorption spectra enables fine-tuning of feature detection in spectrally distinct regions of ...
Ryoko Masuda +3 more
core +1 more source
Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa [PDF]
Dietary flavonoids exhibit many biologically-relevant functions and can potentially have beneficial effects in the treatment of pathological conditions. In spite of its well known antioxidant properties, scarce structural information is available on the ...
Garriga Solé, Pere +5 more
core +3 more sources
The Mongolian gerbil as an advanced model to study cone system physiology
In this work, we introduce a diurnal rodent, the Mongolian gerbil (Meriones unguiculatus) (MG) as an alternative to study retinal cone system physiology and pathophysiology in mice.
Alexander Günter +3 more
doaj +1 more source
Background Intrinsically photosensitive retinal ganglion cells (ipRGCs) drive an array of non-image-forming (NIF) visual responses including circadian photoentrainment and the pupil light reflex.
Edward A. Hayter, Timothy M. Brown
doaj +1 more source
The appearance of rod opsin during monkey retinal development.
To determine the temporal and spatial pattern of rod opsin appearance in Macaca monkey retina.Frozen sections from fetal day (Fd) 55 to adulthood (birth = Fd168) containing the entire horizontal meridian were stained using Rho4D2 monoclonal antiserum visualized with immunofluorescent labeling.
E M, Dorn +2 more
openaire +1 more source
The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein [PDF]
Rapid regeneration of the visual pigment following its photoactivation is critical for the function of cone photoreceptors throughout the day. Though the reactions of the visual cycle in the retinal pigment epithelium (RPE) that recycle chromophore for ...
Crouch, Rosalie K +4 more
core +2 more sources

