Results 101 to 110 of about 6,619 (214)
Calnexin is not essential for mammalian rod opsin biogenesis.
Molecular vision, 2009 Misfolding mutations in rod opsin are a major cause of the inherited blindness retinitis pigmentosa. Therefore, understanding the role of molecular chaperones in facilitating rod opsin biogenesis and the response to mutant rod opsin is important for retinal disease and fundamental retinal cell biology.
Maria, Kosmaoglou, Michael E, Cheetham
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Blue cone monochromacy: visual function and efficacy outcome measures for clinical trials.
PLoS ONE, 2015 BackgroundBlue Cone Monochromacy (BCM) is an X-linked retinopathy caused by mutations in the OPN1LW / OPN1MW gene cluster, encoding long (L)- and middle (M)-wavelength sensitive cone opsins.
Xunda Luo +13 more
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PLoS Medicine, 2006 BackgroundRPE65 is specifically expressed in the retinal pigment epithelium and is essential for the recycling of 11-cis-retinal, the chromophore of rod and cone opsins.
Alexis-Pierre Bemelmans +8 more
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A novel rod‐like opsin isolated from the extra‐retinal photoreceptors of teleost fish
FEBS Letters, 2000 We have isolated a novel opsin from the pineal complex of Atlantic salmon (Salmo salar) and from the brain of the puffer fish (Fugu rubripes). These extra‐retinal opsins share approximately 74% identity at the nucleotide and amino acid level with rod‐opsins from the retina of these species.
Philp, A +3 more
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Localization of complement factor H gene expression and protein distribution in the mouse outer retina. [PDF]
, 2015 To determine the localization of complement factor H (Cfh) mRNA and its protein in the mouse outer retina.Quantitative real-time PCR (qPCR) was used to determine the expression of Cfh and Cfh-related (Cfhr) transcripts in the RPE/choroid.
Estep, Jason +6 more
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STEREOLOGY AND SOME STRUCTURAL CORRELATES OF RETINAL AND PHOTORECEPTOR CELL FUNCTION
Image Analysis and Stereology, 2011 The retina is the part of the eye which detects light, transduces it into nerve impulses and plays a significant role in visual perception. Sensitivity to light is multi-factorial and depends on the properties of photopigment molecules, their synthesis ...
Terry M Mayhew
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BMC Evolutionary Biology, 2017 Background Morphological divergences of snake retinal structure point to complex evolutionary processes and adaptations. The Colubridae family has a remarkable variety of retinal structure that can range from all-cone and all-rod to duplex (cone/rod ...
E. Hauzman +4 more
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Viral Transduction of Human Rod Opsin or Channelrhodopsin Variants to Mouse ON Bipolar Cells Does Not Impact Retinal Anatomy or Cause Measurable Death in the Targeted Cells [PDF]
, 2021 Phillip Wright +5 more
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Functional Properties of Visual Pigments using A1 and A2 Chromophore : From Molecules to Ecology [PDF]
, 2012 The first event in vision is the absorption of a photon by a visual pigment molecule in a retinal photoreceptor cell. Activation of the molecule triggers a chemical amplification cascade, which finally leads to a change in the membrane potential of the ...
Saarinen, Pia
core
Experimental Eye Research, 1989 The distribution of the visual pigment protein opsin in postnatal day 8 and adult rat retinal photoreceptor cells was studied using several well characterized monoclonal antibodies against rhodopsin and a sensitive, modified colloidal gold technique.
D, Hicks, J, Sparrow, C J, Barnstable
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