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Porcine Cytomegalovirus/Porcine Roseolovirus, Previously Transmitted During Xenotransplantation, Does Not Infect Human 293T and Mouse Cells with Impaired Antiviral Defense [PDF]

open access: yesViruses
Porcine cytomegalovirus, more accurately classified as porcine roseolovirus (PCMV/PRV), was shown to be pathogenic in the context of xenotransplantation.
Hina Jhelum   +3 more
doaj   +3 more sources

Mouse Models for Human Herpesviruses [PDF]

open access: yesPathogens, 2023
More than one hundred herpesviruses have been isolated from different species so far, with nine infecting humans. Infections with herpesviruses are characterized by life-long latency and represent a significant challenge for human health.
Ivana Kutle, Anne Dittrich, Dagmar Wirth
doaj   +3 more sources

Transcriptomic profiling of thymic dysregulation and viral tropism after neonatal roseolovirus infection [PDF]

open access: yesFrontiers in Immunology
IntroductionHerpesviruses, including the roseoloviruses, have been linked to autoimmune disease. The ubiquitous and chronic nature of these infections have made it difficult to establish a causal relationship between acute infection and subsequent ...
Andrei Belean   +10 more
doaj   +3 more sources

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders [PDF]

open access: yesFrontiers in Microbiology, 2018
Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty   +11 more
doaj   +5 more sources

Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis [PDF]

open access: yesJournal of Experimental Medicine, 2022
Bigley et al. show that neonatal murine roseolovirus infection disrupts central tolerance. Autoimmunity arises later, in the absence of ongoing infection.
T. Bigley   +5 more
semanticscholar   +3 more sources

A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion [PDF]

open access: yesJournal of Virology, 2017
The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these viruses have been implicated in many
Swapneel J. Patel   +11 more
semanticscholar   +3 more sources

Presence of porcine cytomegalovirus, a porcine roseolovirus, in wild boars in Italy and Germany [PDF]

open access: yesArchives of Virology, 2023
Porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV) that is closely related to human herpesviruses 6 and 7, is commonly found in commercial pigs.
S. Hansen   +6 more
semanticscholar   +3 more sources

Detection of human herpesvirus 6 and 7 DNA in saliva from healthy adults from Rio de Janeiro, Brazil

open access: yesMemorias do Instituto Oswaldo Cruz, 2010
In this study, we aimed to evaluate virus shedding in the saliva of healthy adults from the metropolitan region of the city of Rio de Janeiro, Brazil, in order to verify the prevalence of both human herpesviruses 6 and 7 (HHV-6, HHV-7). The studied group
Ivna M Magalhães   +7 more
doaj   +2 more sources

How Does a Porcine Herpesvirus, PCMV/PRV, Induce a Xenozoonosis. [PDF]

open access: yesInt J Mol Sci
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV), a porcine herpesvirus, has been shown to significantly reduce the survival time of porcine xenotransplants in non-human primates.
Denner J.
europepmc   +3 more sources

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