The chemoprotective hormetic effects of rosmarinic acid [PDF]
Open MedicineRosmarinic acid is a polyphenol found in numerous fruits and vegetables, consumed in supplement form, and tested in numerous clinical trials for therapeutic applications due to its putative chemopreventive properties. Rosmarinic acid has been extensively
Calabrese Edward J. +7 more
doaj +4 more sources
Stability of Rosmarinic Acid in Aqueous Extracts from Different Lamiaceae Species after in vitro Digestion with Human Gastrointestinal Enzymes [PDF]
Food Technology and Biotechnology, 2016 The present study compares the gastrointestinal stability of rosmarinic acid in aqueous extracts of thyme, winter savory and lemon balm with the stability of pure rosmarinic acid.
Zoran Zorić +6 more
doaj +4 more sources
Effect of rosmarinic acid on microbial activity, antioxidant capacity, and metabolite profiles of fermented milk containing Lactiplantibacillus plantarum [PDF]
Food Chemistry: XThis study aimed to elucidate how rosmarinic acid (0, 0.01, 0.03 g/100 mL) affects the microbial activity, antioxidant capacity, and metabolite profiles of fermented milk co-cultured with Lactiplantibacillus plantarum and commercial starter.
Hongwei Yin +4 more
doaj +2 more sources
Rosmarinic Acid Inhibits PRV Replication by Regulating Oxidative Stress Through the Nrf2 Signaling Pathway [PDF]
AnimalsPseudorabies (PR) is an acute and highly contagious disease caused by the pseudorabies virus (PRV). This virus has a wide range of susceptible hosts and has caused major economic losses to the global swine industry.
Ruifei Li +7 more
doaj +2 more sources
Rosmarinic acid ameliorates HCl-induced cystitis in rats.
PLoS ONE, 2023 Shiso (Perilla frutescens var crispa f. purprea) is a traditional medicinal herb that exerts anti-inflammatory effects and alleviates lower urinary tract symptoms. In this study, we examined the effects of rosmarinic acid, a major polyphenol in shiso, on
Naoya Kitamura +3 more
doaj +3 more sources
Antioxidant Activity of Rosmarinic Acid Extracted and Purified from Mentha piperita [PDF]
Archives of Razi Institute, 2021 Rosmarinic acid was obtained from methanolic extract of Mentha piperita L. under a reflux condenser. The current study aimed to evaluate the in vitro antioxidant activities and rosmarinic acid levels of the methanol extracts of M. piperita.
F. E. H Aldoghachi +2 more
doaj +1 more source
Pharmaceutics, 2021 We investigated the involvement of drug transporters in the pharmacokinetics of rosmarinic acid in rats as well as the transporter-mediated drug interaction potential of rosmarinic acid in HEK293 cells overexpressing clinically important solute carrier ...
Yun Ju Kang +5 more
doaj +1 more source
Biomolecules, 2021 Rosmarinic acid, a major component of rosemary, is a polyphenolic compound with potential neuroprotective effects. Asreducing the synaptic release of glutamate is crucial to achieving neuroprotectant’s pharmacotherapeutic effects, the effect of ...
Che-Chuan Wang +3 more
doaj +1 more source
Application of Rosmarinic Acid with Its Derivatives in the Treatment of Microbial Pathogens
Molecules, 2023 The emergence of the antimicrobial resistance phenomena on and the harmful consequences of the use of antibiotics motivate the necessity of innovative antimicrobial therapies, while natural substances are considered a promising alternative.
Ourdia-Nouara Kernou +3 more
doaj +1 more source
Rosmarinic Acid–Human Pharmacokinetics and Health Benefits [PDF]
Planta Medica, 2020 AbstractRosmarinic acid is a phenolic compound commonly found in the Lamiaceae (Labiateae) plant species. It is considered responsible for a wide spectrum of biological and pharmacological activities of plants containing this compound. The aim of the current review is to present the fate of rosmarinic acid inside the human body, explained through ...
Maja Hitl +3 more
openaire +2 more sources