Results 31 to 40 of about 64,618 (285)

Magnolol as a Protective Antioxidant Alleviates Rotenone-Induced Oxidative Stress and Liver Damage through MAPK/mTOR/Nrf2 in Broilers

Metabolites, 2023
This study aimed to investigate the protective effects and molecular mechanism of magnolol supplementation on rotenone-induced oxidative stress in broilers. Two hundred and eighty-eight old male AA broilers were randomly divided into four groups: the CON
Weishi Peng, Nanxuan Zhou, Zehe Song, Haihan Zhang, Xi He   +4 more
doaj   +1 more source

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 [PDF]

, 2014
The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear.
Billen, Johan, Braeckman, Bart, De Haes, Wouter, Depuydt, Geert, Frooninckx, Lotte, Schoofs, Liliane, Smolders, Arne, Temmerman, Liesbet, Van Assche, Roel   +8 more
core   +1 more source

Effects of Low Concentrations of Rotenone Upon Mitohormesis in SH-SY5Y Cells

Dose-Response, 2013
The mitochondrial toxin rotenone exerts cytotoxicity via overproduction of reactive oxygen species (ROS) and depolarization of the mitochondrial membrane.
Xiong Yuyun, Qian Jinjun, Xu Minfang, Qiu Jing, Xia Juan, Ma Rui, Zhu Li, Gao Jing   +7 more
doaj   +1 more source

A highly reproducible rotenone model of Parkinson's disease

Neurobiology of Disease, 2009
The systemic rotenone model of Parkinson's disease (PD) accurately replicates many aspects of the pathology of human PD and has provided insights into the pathogenesis of PD.
Jason R. Cannon, Victor Tapias, Hye Mee Na, Anthony S. Honick, Robert E. Drolet, J. Timothy Greenamyre   +5 more
doaj   +1 more source

Wirkung verschiedener Insektizide und Repellentien gegen den Gemeinen Birnenblattsauger (Cacopsylla pyri) [PDF]

, 2004
The efficacy of different insecticides (neem, pyrethrin, spinosad, and rotenone) and a repellent (kaolin) applied with different strategies (single or repeated applications) against the over-wintering pear suckers (Cacopsylla pyri) and nymphs of the ...
Daniel, Claudia, Wyss, Eric
core  

Serine one-carbon catabolism with formate overflow [PDF]

, 2016
Serine catabolism to glycine and a one-carbon unit has been linked to the anabolic requirements of proliferating mammalian cells. However, genome-scale modeling predicts a catabolic role with one-carbon release as formate. We experimentally prove that in
Athineos, Dimitris, Blyth, Karen, Gottlieb, Eyal, Kamphorst, Jurre J., Labuschagne, Christiaan Fred, Mackay, Gillian M., Maddocks, Oliver, Meiser, Johannes, Tumanov, Sergey, Van Den Broek, Niels, Vazquez, Alexei, Vousden, Karen   +11 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Effect of rotenone-induced stress on physiologically active substances in adult Aphis glycines.

PLoS ONE, 2020
The aim of this study was to determine the effect of rotenone stress on Aphis glycines Matsumura (Hemiptera: Aphididae) populations in different habitats of Northeast China.
Lanlan Han, Litong Gao, Ziru Hao, Kuijun Zhao, Wenlin Zhang, Juan Chen, Jianfei Xiao, Aonan Zhang, Zhenghao Shi, Lin Zhu   +9 more
doaj   +1 more source

PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration

Ecotoxicology and Environmental Safety, 2023
Rotenone, a widely used pesticide, causes dopaminergic neurons loss and increase the risk of Parkinson's disease (PD). However, few studies link the role of PARP1 to neuroinflammatory response and autophagy dysfunction in rotenone-induced ...
He Zhang, Zhefan Xie, Yongming Peng, Ailun Xie, Chunlai Fu, Dongyan Zheng, ZiWei Cai, Jiahong Zhong, Qiang Ming, Mingque Li, Renjian Lu, Xin Liu, Jialong Chen   +12 more
doaj   +1 more source

Efficacy of different insecticides and a repellent against the European pear sucker (Cacopsylla pyri) [PDF]

, 2004
The efficacy of different insecticides (neem, pyrethrin, spinosad, and rotenone) and a repellent (kaolin) applied with different strategies (single or repeated applications) against the over-wintering pear suckers (Cacopsylla pyri) and nymphs of the ...
Daniel, Claudia, Wyss, Eric
core