Results 61 to 70 of about 35,461 (280)

Analysis of Vibrant Soundbridge placement against the round window membrane in a human cadaveric temporal bone model. [PDF]

, 2010
Contains fulltext : 88166.pdf (Publisher’s version ) (Open Access)OBJECTIVE: To evaluate optimal placement of the Floating Mass Transducer of the Vibrant Soundbridge (Med-El, Innsbruck, Austria) against the round window membrane ...
Manohar Bance, Bance, M., Wijhe, R.G. van, Ho, A., René G. van Wijhe, Ronald J. E. Pennings, Allan Ho, Pennings, R.J.E., Jeremy Brown, Brown, J.   +9 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Anatomical and Surgical Evaluation of the Common Marmoset as an Animal Model in Hearing Research

Frontiers in Neuroanatomy, 2019
Recent studies have indicated that direct administration of viral vectors or small compounds to the inner ear may aid in the treatment of Sensorineural hearing loss (SNHL).
Sho Kurihara, Sho Kurihara, Masato Fujioka, Junichi Hata, Tomohiko Yoshida, Motoki Hirabayashi, Motoki Hirabayashi, Yutaka Yamamoto, Kaoru Ogawa, Hiromi Kojima, Hirotaka James Okano   +10 more
doaj   +1 more source

Ways of penetration of glucocorticosteroids from the tympanic cavity to the structures of the inner ear: A review

Consilium Medicum, 2022
To date, in domestic and foreign literature, there are more and more reports of the successful use of glucocorticosteroids for the treatment of pathology of the inner ear by local intratympanic administration. Many methods are being developed to deliver
Marina L. Blinova, Andrei E. Golovanov, Vadim S. Isachenko   +2 more
doaj   +1 more source

The implanted round window membrane in the cat [Abstract] [PDF]

, 1983
This is an abstract of a paper presented at a symposium on the Mechanisms of Hearing, held at Monash University, Melbourne, Australia from August 23-27, 1983.
Bloom, D., Clark, Graeme M., Franz, B., Ng, J.   +3 more
core  

Round window membrane motion with air conduction and bone conduction stimulation [PDF]

, 2004
The vibration patterns of the round window (RW) membrane in human cadaver temporal bone specimens were assessed by measurements of the velocity of reflective targets placed on the RW membrane with an approximate spacing of 0.2 mm.
Stenfelt, Stefan, Goode, R.L., Hato, N,, Goode, RL,, Hato, N., Stenfelt, Stefan,   +5 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Immunodefense of the round window [PDF]

, 2008
A systematic analysis using serial sectioning of the round window membrane (RWM) in the cynomolgus monkey was performed. Light and transmission electron microscopy (LM and TEM) revealed that the RWM rim may be endowed with gland-like structures with ...
Laurell, G,, Laurell, Göran,, Bagger-Sjobadck, D, Bagger-Sjöbäck, Dan, Rask-Andersen, H, Rask-Andersen, Helge,, Engmer, C, Engmér, Cecilia   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Selected parameters for the cochlear model (x is in meters measured from the base of the cochlea). BM: basilar membrane. HB: hair bundle. MET: Mechanoelectrical transducer. OW: Oval window. RW: Round window. [PDF]

, 2016
Selected parameters for the cochlear model (x is in meters measured from the base of the cochlea). BM: basilar membrane. HB: hair bundle. MET: Mechanoelectrical transducer. OW: Oval window. RW: Round window.
Yizeng Li (3159243), Karl Grosh (3159240)   +1 more
core   +1 more source