Results 71 to 80 of about 35,461 (280)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Scientific ReportsSound transmission to the human inner ear by bone conduction pathway with an implant attached to the otic capsule is a specific case where the cochlear response depends on the direction of the stimulating force.
Paweł Borkowski
doaj +1 more source
Segmentation and reconstruction of the 3D geometry of the middle and inner ear
ITM Web of Conferences, 2017 The anatomical model of the ear is of great importance in the design of ossicular prosthesis, cochlear implant electrodes, as well as for the preoperative planning and navigation of surgery. By means of micro-computed tomography (micro-CT) and technology
Lu Yanfei
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Measurements of round window membrane vibrations with use of Laser Doppler Vibrometer [PDF]
, 2011 W artykule opisano wykonane po raz pierwszy w Polsce bezkontaktowe pomiary parametrów drgań błony okienka okrągłego (RW) w świeżych preparatach ludzkiej kości skroniowej wykonane metodą laserowej wibrometrii Dopplerowskiej (LDV).
Wysocki, J., Kwacz, M., Mrówka, M.
core
Conditions for Highly Efficient and Reproducible Round-Window Stimulation in Humans [PDF]
, 2011 Round-window stimulation is a new clinical approach for the application of active middle-ear implants. To investigate factors influencing the efficiency of round-window stimulation, experiments in 6 human temporal bones were performed with different ...
Erich Goll +6 more
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Long-term outcome of round window vibrant soundbridge implantation in extensive ossicular chain defects [PDF]
, 2013 Objective. To evaluate retrospectively the long-term safety and efficacy of the first 50 patients, all suffering from severe ossicular chain defects and with moderate to severe mixed hearing loss, who received the Vibrant SoundBridge with the floating ...
Liliana Colletti +5 more
core +4 more sources
Anatomic Considerations on the Middle Ear in Dog
Scientific Papers Animal Science and Biotechnologies, 2023 Purpose of this study is to explain some aspects of middle ear anatomy in dog. The study was conducted on five dog skulls (different ages) from common, large size dogs.
Carmen Berghes +3 more
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