Results 191 to 200 of about 97,740 (305)

DETERMINATION OF ETODOLAC BY RP-HPLC METHOD

open access: yesInternational Research Journal Of Pharmacy, 2020
Vaibhav Gulabrao Bhamare   +1 more
openaire   +1 more source

The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae

open access: yesTraffic, Volume 27, Issue 2, June 2026.
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhibits vacuolar fragmentation, enlarged lipid droplets, and metabolic alterations. Ruiz Salas, J. L. (2026) https://BioRender.com/b65g523. ABSTRACT Erv14 is a
Paul Rosas‐Santiago   +12 more
wiley   +1 more source

Metal Ion Binding of Vimentin Tail Domain Fragments

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
An investigation of the structural and metal‐binding properties of the isolated vimentin tail domain was performed. The affinity and location of Cu(II) binding to both peptide and protein fragments of the tail domain of vimentin were characterized, providing a foundation for exploring how metals drive conformational change in vimentin intermediate ...
Estely J. Carranza   +2 more
wiley   +1 more source

Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation

open access: yesChemMedChem, Volume 21, Issue 9, 14 May 2026.
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga   +11 more
wiley   +1 more source

One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy